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Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01873 | -- | $-- |
Alkyne-PEG5-SNAP is a versatile chemical reagent used predominantly in bioconjugation and labeling applications. Here are some key applications of Alkyne-PEG5-SNAP:
Protein Labeling: Alkyne-PEG5-SNAP is widely used for site-specific labeling of proteins in biochemical and cellular studies. The SNAP-tag technology allows for efficient and selective covalent attachment of the Alkyne-PEG5 moiety to SNAP-tagged proteins. This enables the subsequent conjugation of various probes or fluorophores via click chemistry, aiding in protein tracking, localization, and interaction studies in live cells.
Drug Delivery: Alkyne-PEG5-SNAP can be employed in the development of targeted drug delivery systems. By conjugating therapeutic agents to SNAP-tagged proteins or peptides, researchers can achieve precise delivery to specific cell types or tissues. The PEGylation aspect of Alkyne-PEG5 enhances the solubility and stability of the conjugates, ultimately improving the pharmacokinetic properties of the drug.
Cell Surface Engineering: Alkyne-PEG5-SNAP is utilized in cell surface engineering to modify the cellular membrane with bioactive molecules. This technique involves labeling cell surface proteins with SNAP-tag and subsequently reacting them with Alkyne-PEG5 for click chemistry reactions. Such modifications can be used to study cell signaling, adhesion, and interactions with the extracellular environment, and for developing cell-based biosensors.
Biocompatible Hydrogels: Alkyne-PEG5-SNAP can be used in the fabrication of biocompatible hydrogels for tissue engineering and regenerative medicine applications. By incorporating Alkyne-PEG5 into hydrogel scaffolds, researchers can create highly tunable materials that support cell growth and differentiation. The SNAP-tag allows for functionalization with bioactive molecules, enhancing the hydrogels’ capabilities as cell culture platforms or implantable materials.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
