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| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01094 | -- | $-- | Inquiry |
mDPR(Boc)-Val-Cit-PAB, a specialized linker molecule utilized in drug development, particularly in the creation of antibody-drug conjugates (ADCs), boasts a diverse array of applications.
Antibody-Drug Conjugate Development: An integral component in the realm of ADC development, mDPR(Boc)-Val-Cit-PAB serves as the linchpin connecting potent cytotoxic drugs to specific antibodies. Engineered for stability in the bloodstream yet enabling precise drug release within target cancer cells, this linker facilitates targeted delivery, thus minimizing systemic toxicity and amplifying therapeutic efficacy.
Cancer Research: In the expansive landscape of cancer research, mDPR(Boc)-Val-Cit-PAB takes center stage as a tool for dissecting targeted drug delivery mechanisms. Researchers harness this linker to scrutinize the ability of ADCs to selectively transport chemotherapy drugs to cancerous cells while sparing healthy tissues. These inquiries are pivotal in advancing the development of safer and more potent cancer therapies.
Bioconjugation Techniques: At the nexus of bioconjugation techniques, mDPR(Boc)-Val-Cit-PAB emerges as a pivotal facilitator for attaching diverse bioactive molecules to antibodies or other targeting entities. Its versatility empowers the creation of intricate bioconjugates with far-reaching implications across diagnostics, therapeutic monitoring, and personalized medicine. This linker enhances the functional repertoire of conjugated molecules, broadening their applications in the dynamic realm of biomedical research.
Pharmaceutical Manufacturing: Within the sphere of pharmaceutical manufacturing, mDPR(Boc)-Val-Cit-PAB assumes a critical role in the synthesis of stable and efficacious drug conjugates. This linker guarantees the secure attachment of payloads during production, ensuring their integrity through formulation and storage. Such stability is paramount for upholding the potency and consistency of the final therapeutic product, thereby securing reliable and robust clinical outcomes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
