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Azido-C6-OH

  CAS No.: 146292-90-2   Cat No.: BADC-01513 4.5  

Azido-C6-OH is a valuable chemical compound used in biomedicine. This product is commonly employed as a reactive probe for labeling and imaging biomolecules. It is specifically used in the research and development of targeted drug delivery systems and studies related to bioconjugation and click chemistry. With its unique properties, Azido-C6-OH plays a crucial role in advancing drug discovery and diagnostics for various diseases.

Azido-C6-OH

Structure of 146292-90-2

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Molecular Formula
C6H13N3O
Molecular Weight
143.19

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
6-azidohexan-1-ol; 1-Hexanol, 6-azido-; 6-azido-1-hexanol; Azido-C6-OH; 6-azidohexanol; 1-azido-6-hydroxyhexane
IUPAC Name
6-azidohexan-1-ol
Canonical SMILES
C(CCCO)CCN=[N+]=[N-]
InChI
InChI=1S/C6H13N3O/c7-9-8-5-3-1-2-4-6-10/h10H,1-6H2
InChIKey
WHYHCPIPOSTZRU-UHFFFAOYSA-N

Azido-C6-OH is a versatile compound often used in advanced biochemical research and technology. Here are some key applications of Azido-C6-OH:

Click Chemistry: Azido-C6-OH is widely used in click chemistry for bioconjugation and labeling applications. By incorporating azide groups into biomolecules, researchers can selectively attach various probes and tags using copper-catalyzed or strain-promoted azide-alkyne cycloaddition reactions. This allows for the precise and efficient labeling of proteins, nucleic acids, and other biomolecules for imaging and functional studies.

Drug Delivery Systems: Azido-C6-OH can be employed in the development of targeted drug delivery systems. The azide group allows for the attachment of drug molecules to carriers, such as nanoparticles or liposomes, through click chemistry. This targeted approach facilitates the delivery of therapeutics to specific tissues or cells, potentially enhancing treatment efficacy and reducing side effects.

Proteomics: In proteomics, Azido-C6-OH can be utilized for identifying and characterizing protein interactions and modifications. By incorporating azide tags into proteins, researchers can use click chemistry to pull down protein complexes and analyze them via mass spectrometry or other analytical techniques. This application provides insights into protein networks, post-translational modifications, and cellular mechanisms.

Bioorthogonal Chemistry: Azido-C6-OH is essential in bioorthogonal chemistry, which involves chemical reactions that occur inside living organisms without interfering with native biochemical processes. By utilizing the highly specific azide-alkyne click reaction, researchers can probe and manipulate biological systems with minimal perturbation.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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