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Biotin-sar-oh is a cleavable linker widely used in conjugated drug development. It has ultra-modern applicability as a targeted therapeutic adjunct that selectively binds to malignant cellular entities and strongly inhibits their proliferative activity.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01518 | -- | $-- | Inquiry |
Biotin-sar-oh, a widely utilized biochemical tool in diverse biological and clinical research settings, offers a multitude of applications. Here are four key applications of Biotin-sar-oh presented with heightened perplexity and burstiness:
Protein Labeling: Within the realm of protein labeling, Biotin-sar-oh serves as a pivotal component, covalently binding to proteins and facilitating subsequent detection with ease. This functionality proves essential in assays such as western blotting and immunohistochemistry, where precise identification and quantification of specific proteins are paramount. Through the attachment of biotin to proteins, researchers can employ streptavidin-based techniques to visualize or purify proteins of interest, enriching the investigative process.
Cell Surface Biotinylation: In the intricate field of cell biology, Biotin-sar-oh finds application in the labeling of cell surface proteins, while ensuring maintained cell viability. This methodology enables the exploration of cell surface protein interactions, receptor trafficking dynamics, and intricate cell signaling pathways. By biotinylating cell surface proteins, researchers can extract and analyze these proteins utilizing streptavidin-based affinity methodologies, shedding light on fundamental cellular processes with intricate detail.
Molecular Imaging: At the forefront of molecular imaging techniques, Biotin-sar-oh assumes a critical role in targeting and visualizing molecular structures within cellular and tissue environments. Notably, biotinylated antibodies, in conjunction with labeled streptavidin, are instrumental in the detection of specific antigens within tissues, a pivotal application for diagnostic purposes and enhancing comprehension of molecular distribution and localization within biological systems.
Enzyme Activity Assays: Biotin-sar-oh emerges as a key player in diverse enzyme activity assays, facilitating the monitoring of biotinylated enzyme functionality. Through the conjugation of biotin to substrates or inhibitors, researchers can delve into enzyme kinetics and interactions with exceptional specificity, offering profound insights into enzyme functions. This understanding not only aids in unraveling enzyme mechanisms, but also fosters the development of enzyme inhibitors for potential therapeutic interventions, showcasing the versatility and significance of Biotin-sar-oh in enzymology research.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
