Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity.
Structure of 474645-27-7
* For research and manufacturing use only. We do not sell to patients.
Size | Price | Stock | Quantity |
---|---|---|---|
25 mg | $298 | In stock |
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Capabilities & Facilities
NCT Number | Condition Or Disease | Phase | Start Date | Sponsor | Status |
---|---|---|---|---|---|
NCT05113459 | Gastric Cancer | Phase 2 | 2021-11-09 | Guoxin Li | Not yet recruiting |
NCT03187210 | Lymphoma | Phase 1, Phase 2 | 2021-08-05 | University Hospital Inselspital, Berne | Recruiting |
NCT04679012 | Richter Syndrome | Phase 2 | 2021-09-22 | Weill Medical College of Cornell University | Not yet recruiting |
NCT05006664 | Lymphoma, T-Cell, Peripheral | Phase 2 | 2021-09-01 | Czech Lymphoma Study Group | Not yet recruiting |
NCT02227433 | Hodgkin Lymphoma | Phase 2 | 2020-12-22 | Fondazione Italiana Linfomi ONLUS | Completed |
Catalog | Product Name | CAS | Inquiry |
---|---|---|---|
BADC-00019 | Fmoc-VC-PAB-MMAE | 1350456-56-2 | |
BADC-00849 | Acetylene-linker-Val-Cit-PABC-MMAE | 1411977-95-1 | |
BADC-01448 | mDPR-Val-Cit-PAB-MMAE | 1491152-26-1 | |
BADC-00958 | Amino-PEG4-Val-Cit-PAB-MMAE | 1492056-71-9 | |
BADC-01348 | Val-Cit-PAB-MMAE TFA salt | 1608127-32-7 | |
BADC-01435 | N-Ac-Cys-MC-VC-PAB-MMAE | 1628933-80-1 | |
BADC-01408 | DBM(C6)-VC-PAB-MMAE | 1644228-55-6 | |
BADC-01459 | MC-betaglucuronide-MMAE-1 | 1703778-92-0 | |
BADC-01638 | OH-Glu-Val-Cit-PAB-MMAE | 1895916-23-0 | |
BADC-00855 | SuO-Glu-Val-Cit-PAB-MMAE | 1895916-24-1 |
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