Methyltetrazine-SS-NHS

Methyltetrazine-SS-NHS, a reactive compound at the forefront of bioorthogonal chemistry, is primarily utilized for its labeling and conjugation applications.

Bioconjugation: Embracing the innovative realm of bioorthogonal chemistry, Methyltetrazine-SS-NHS serves as a pivotal component in the creation of stable bioconjugates through the tetrazine-trans-cyclooctene (TCO) ligation reaction. This reaction, specific and rapid, unfolds without the reliance on metal catalysts, allowing for the seamless labeling of biomolecules even within complex environments. Notably, it finds significant utility in crafting antibody-drug conjugates tailored for targeted cancer therapies.

Fluorescent Labeling: Illuminating the path in fluorescence microscopy and imaging endeavors, Methyltetrazine-SS-NHS emerges as a key player in labeling proteins and other biomolecules with fluorescent dyes. By facilitating the precise attachment of fluorophores to designated sites, it empowers researchers to witness dynamic cellular processes unfold in real-time, enabling the detailed exploration of protein interactions and cellular trafficking dynamics, ushering in a deeper understanding of the intricate machinery of life.

Site-specific Protein Modification: Unlocking new dimensions in bioanalytical exploration, Methyltetrazine-SS-NHS facilitates the targeted modification of proteins at specific sites, crucial for unraveling the complexities of protein functionalities and structures. This technique fuels the creation of modified proteins instrumental in elucidating intricate protein-protein interactions and enzymatic activities, thereby bolstering the development of cutting-edge bioanalytical tools and potential therapeutic agents.