Methyltetrazine-SS-NHS

Methyltetrazine-SS-NHS Catalog number: BADC-01292

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Category
ADCs Linker
Product Name
Methyltetrazine-SS-NHS
Catalog Number
BADC-01292
Molecular Formula
C20H22N6O5S2
Molecular Weight
490.56
Purity
≥95%

Ordering Information

Catalog Number Size Price Quantity
BADC-01292 -- $-- Inquiry
Solubility
10 mm in DMSO
Shelf Life
≥ 2 years
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

Methyltetrazine-SS-NHS, a reactive compound at the forefront of bioorthogonal chemistry, is primarily utilized for its labeling and conjugation applications.

Bioconjugation: Embracing the innovative realm of bioorthogonal chemistry, Methyltetrazine-SS-NHS serves as a pivotal component in the creation of stable bioconjugates through the tetrazine-trans-cyclooctene (TCO) ligation reaction. This reaction, specific and rapid, unfolds without the reliance on metal catalysts, allowing for the seamless labeling of biomolecules even within complex environments. Notably, it finds significant utility in crafting antibody-drug conjugates tailored for targeted cancer therapies.

Fluorescent Labeling: Illuminating the path in fluorescence microscopy and imaging endeavors, Methyltetrazine-SS-NHS emerges as a key player in labeling proteins and other biomolecules with fluorescent dyes. By facilitating the precise attachment of fluorophores to designated sites, it empowers researchers to witness dynamic cellular processes unfold in real-time, enabling the detailed exploration of protein interactions and cellular trafficking dynamics, ushering in a deeper understanding of the intricate machinery of life.

Site-specific Protein Modification: Unlocking new dimensions in bioanalytical exploration, Methyltetrazine-SS-NHS facilitates the targeted modification of proteins at specific sites, crucial for unraveling the complexities of protein functionalities and structures. This technique fuels the creation of modified proteins instrumental in elucidating intricate protein-protein interactions and enzymatic activities, thereby bolstering the development of cutting-edge bioanalytical tools and potential therapeutic agents.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Methyltetrazine-SS-NHS
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