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CAS No.:
Cat No.: BADC-01237
Purity: >98.0%
4.5 
Boc-amino-PEG3-SSPy is a cleavable, Boc-protected PEG linker containing disulfide and pyridyl disulfide groups, designed for redox-sensitive drug release in antibody-drug conjugates.
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Boc-amino-PEG3-SSPy is a bifunctional crosslinker with a protected amine group (Boc) and a pyridyl disulfide group (SSPy) separated by a polyethylene glycol (PEG) spacer. Here are some key applications of Boc-amino-PEG3-SSPy:
Protein Conjugation: Boc-amino-PEG3-SSPy is widely used for protein conjugation, enabling the attachment of therapeutic agents, fluorescent probes, or other biomolecules to proteins. The PEG spacer provides flexibility and reduces steric hindrance, improving the stability and function of the conjugated proteins. These conjugates are essential in developing targeted drug delivery systems and diagnostic assays.
Biomolecular Crosslinking: Boc-amino-PEG3-SSPy serves as a versatile crosslinking reagent in the preparation of multifunctional biomolecular assemblies. By linking proteins, peptides, or other biomolecules, it facilitates the study of protein-protein interactions and the creation of complex biomaterials. The reversible nature of the disulfide bond allows for controlled assembly and disassembly.
Surface Modification: Boc-amino-PEG3-SSPy can be used to modify surfaces of biomaterials, enhancing their biocompatibility and functional properties. The PEG spacer helps in reducing non-specific binding and improving bioavailability. Functionalized surfaces are valuable in biosensors, tissue engineering, and medical implants.
Drug Delivery Systems: This compound is employed in the design of advanced drug delivery systems by acting as a linker between drug molecules and delivery carriers. The attachment of Boc-amino-PEG3-SSPy to drugs and their carriers can improve the pharmacokinetics and targeted delivery of therapeutic agents. Such systems are pivotal for improving treatment efficacy and reducing adverse effects.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01236 | Boc-amino-PEG3-SS-acid |
Boc-amino-PEG3-SSPy
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Boc-amino-PEG3-SSPy
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