Methyltetrazine-DBCO - CAS 1802238-48-7

Methyltetrazine-DBCO - CAS 1802238-48-7 Catalog number: BADC-00994

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category
ADCs Linker
Product Name
Methyltetrazine-DBCO
CAS
1802238-48-7
Catalog Number
BADC-00994
Molecular Formula
C34H33N7O7S
Molecular Weight
683.73
Purity
>98.0%
Methyltetrazine-DBCO

Ordering Information

Catalog Number Size Price Quantity
BADC-00994 -- $-- Inquiry
Synonyms
3-[[4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-4-oxobutanoyl]amino]-1-[3-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]propylamino]-1-oxopropane-2-sulfonic acid; 2-(4-{2-azatricyclo[10.4.0.0,hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-4-oxobutanamido)-1-({3-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]propyl}carbamoyl)ethane-1-sulfonic acid
Canonical SMILES
CC1=NN=C(N=N1)C2=CC=C(C=C2)OCCCNC(=O)C(CNC(=O)CCC(=O)N3CC4=CC=CC=C4C#CC5=CC=CC=C53)S(=O)(=O)O
InChI
InChI=1S/C34H33N7O7S/c1-23-37-39-33(40-38-23)26-13-15-28(16-14-26)48-20-6-19-35-34(44)30(49(45,46)47)21-36-31(42)17-18-32(43)41-22-27-9-3-2-7-24(27)11-12-25-8-4-5-10-29(25)41/h2-5,7-10,13-16,30H,6,17-22H2,1H3,(H,35,44)(H,36,42)(H,45,46,47)
InChIKey
YYYPWVPKWWTZRY-UHFFFAOYSA-N
Solubility
10 mm in DMSO
Appearance
Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Form
Solid

Methyltetrazine-DBCO, a versatile chemical compound utilized in bioorthogonal chemistry for labeling and conjugation, offers a plethora of applications.

Bioconjugation Techniques: Leveraging Methyltetrazine-DBCO, scientists can achieve site-specific biomolecule conjugation through the rapid tetrazine ligation—a bioorthogonal reaction that ensures precise labeling of proteins, nucleic acids, or small molecules without disrupting biological systems. This technique is invaluable for creating bioconjugates tailored for diagnostic and therapeutic uses.

Live-Cell Imaging: Methyltetrazine-DBCO's exceptional characteristics make it an indispensable tool for live-cell imaging endeavors. By fluorescently tagging live cells using the tetrazine ligation, researchers can dynamically visualize cellular processes in real time, enhancing the study of biological events without perturbing normal cellular functions.

In Vivo Tracking: The utilization of Methyltetrazine-DBCO for in vivo biomolecule tracking in animal models is paramount. Through conjugation with imaging agents, scientists can monitor the distribution and accumulation of labeled molecules within live organisms, offering insights into biodistribution, pharmacokinetics, and the efficacy of drug candidates—an essential aspect of drug development.

Targeted Drug Delivery: Methyltetrazine-DBCO plays a pivotal role in enabling targeted drug delivery by selectively conjugating therapeutic agents to carrier molecules or targeting moieties. This approach enhances the precise delivery of drugs to diseased tissues or cells, mitigating off-target effects and optimizing therapeutic outcomes. Such innovative strategies are instrumental in designing sophisticated drug delivery systems for combating diseases like cancer.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Methyltetrazine-DBCO
Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket