Name: H-L-Phe(4-NH-Poc)-OH HCl
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

H-L-Aph(Poc)-OH HCl; H-Phe(4-NH-Poc).HCl; H-4Aph(Poc) HCl; H-L-4Aph(Poc)-OH HCl; H-L-4-Aph(Poc)-OH HCl; H-p-amino-Phe(Poc)-OH HCl; H-L-Phe(4-NH-Pryoc)-OH HCl; H-4Aph(Pryoc) HCl; H-L-4Aph(Pryoc)-OH HCl; H-L-4-Aph(Pryoc)-OH HCl; H-p-amino-Phe(Pryoc)-OH HCl; (1S)-1-carboxy-2-(4-{[(prop-2-yn-1-yloxy)carbonyl]amino}phenyl)ethan-1-aminium chloride; L-Phenylalanine, 4-[[(2-propyn-1-yloxy)carbonyl]amino]-, hydrochloride (1:1); 4-(Propargyloxycarbonyl)amino-L-phenylalanine hydrochloride; H-L-Phe(4-NH-Poc)-OH hydrochloride

IUPAC Name

(2S)-2-amino-3-[4-(prop-2-ynoxycarbonylamino)phenyl]propanoic acid;hydrochloride

Canonical SMILES

C#CCOC(=O)NC1=CC=C(C=C1)C[C@@H](C(=O)O)N.Cl

InChI

InChI=1S/C13H14N2O4.ClH/c1-2-7-19-13(18)15-10-5-3-9(4-6-10)8-11(14)12(16)17;/h1,3-6,11H,7-8,14H2,(H,15,18)(H,16,17);1H/t11-;/m0./s1

InChIKey

PKNZLMSSIPKCPT-MERQFXBCSA-N

Storage

Store at 2-8 °C

H-Phe(4-NH-Poc) HCl, a versatile chemical compound, finds diverse applications in the realm of bioscience. Here are four key applications of H-Phe(4-NH-Poc) HCl:

Peptide Synthesis: H-Phe(4-NH-Poc) HCl plays a crucial role in crafting peptides and oligopeptides. Serving as a protective shield for the amine group of phenylalanine, it shields against undesired reactions during peptide coupling. This meticulous process ensures the synthesis of peptides with exceptional purity and precise sequences, which are indispensable for both research and therapeutic endeavors.

Drug Development: In pharmaceuticals, H-Phe(4-NH-Poc) HCl emerges as a key player in peptide-based drug development. Essential for creating complex peptide sequences step by step, protective agents like H-Phe(4-NH-Poc) pave the way for innovative peptide therapeutics targeting a spectrum of diseases, from cancer and diabetes to infectious ailments. This intricate synthesis process holds promise for groundbreaking advancements in medical treatments.

Bioconjugation: Delving into bioconjugation techniques, H-Phe(4-NH-Poc) HCl facilitates the fusion of peptides with diverse molecules like proteins, antibodies, or nanoparticles. This fusion is pivotal for the development of cutting-edge diagnostic tools and precision-targeted drug delivery systems. Leveraging the stability and functional enhancement offered by H-Phe(4-NH-Poc) ensures the efficacy of these conjugated peptides in various biomedical applications.

Proteomic Research: At the forefront of proteomics, H-Phe(4-NH-Poc) HCl takes center stage in preparing labeled peptides for mass spectrometry analysis. Its protective group aids in the selective modification of peptides, enabling accurate identification and quantification of proteins in intricate biological samples. This application holds profound importance in deciphering protein functions, interactions, and dynamics within cellular environments, shedding light on the intricacies of biological systems.