DBCO-acid - CAS 1353016-70-2

DBCO-acid - CAS 1353016-70-2 Catalog number: BADC-00932

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DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690).

General Information

Category
ADCs Linker
Product Name
DBCO-acid
CAS
1353016-70-2
Catalog Number
BADC-00932
Molecular Formula
C19H15NO3
Molecular Weight
305.33 g/mol

Chemical Structure

  • DBCO-acid
Purity
>98.0%
Synonyms
11,12-Didehydro-gamma-oxodibenz[b,f]azocine-5(6H)-butanoic acid
Solubility
10 mM in DMSO
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Application
White to light yellow powder to crystal
Shelf Life
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Shipping
-20°C (International: -20°C)
Melting Point
179.0 to 183.0 °C
Canonical SMILES
C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCC(=O)O
InChI Key
NDLOVDOICXITOK-UHFFFAOYSA-N
InChI
InChI=1S/C19H15NO3/c21-18(11-12-19(22)23)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13H2,(H,22,23)
Form
Solid
BiologicalActivity
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and druglinker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1] .

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Historical Records: Propybicyphat | Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA | Cynaroside | Apamin | BOMIN-2 | Tetrazine-SS-NHS | Mesaconitine | BCN-PEG1-Val-Cit-OH | Leucomisine | Fmoc-D-Val-D-Cit-PAB | DBCO-acid
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