H-(Gly)3-Lys(N3)-OH is a glycine-tripeptide azide-functionalized ADC linker intermediate facilitating precise bioorthogonal conjugation in antibody-drug conjugates for stable and site-specific payload attachment. Keywords: ADC linker, peptide linker, azide linker, bioorthogonal chemistry, targeted delivery.
Structure of 2250437-45-5
* For research and manufacturing use only. We do not sell to patients.
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Capabilities & Facilities
H-(Gly)3-Lys(N3)-OH, a synthetic peptide featuring an azido group, presents a myriad of potential applications in biochemical research and biotechnology.
Bioorthogonal Chemistry: In the realm of bioorthogonal chemistry, H-(Gly)3-Lys(N3)-OH emerges as a versatile tool for labeling and tracing biomolecules within living systems. The azido group within this peptide engages in click chemistry reactions with alkyne-containing molecules, allowing for precise labeling without disrupting natural biological processes.
Peptide Conjugation: With its azido group, H-(Gly)3-Lys(N3)-OH stands out as a prime candidate for peptide conjugation, offering researchers the opportunity to attach various functional groups or molecules, such as fluorophores or drugs, through click chemistry. This versatility proves invaluable for designing multifunctional peptides tailored for diagnostic and therapeutic applications, showcasing the peptide’s adaptability in diverse settings.
Proteomics: Within the domain of proteomics studies, H-(Gly)3-Lys(N3)-OH finds utility in integrating labels into proteins for mass spectrometry analysis. The azido group enables the selective and efficient attachment of isotopic labels, enhancing the identification and quantification of proteins. This method plays a pivotal role in characterizing proteomes in detail and shedding light on the dynamic expression patterns of proteins.
Catalog | Product Name | CAS | Inquiry |
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BADC-01846 | H-(Gly)3-Lys(N3)-OH HCl | 2737202-70-7 |
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