webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

H-(Gly)3-Lys(N3)-OH

  CAS No.: 2250437-45-5   Cat No.: BADC-01769   Purity: >96% 4.5  

H-(Gly)3-Lys(N3)-OH is a glycine-tripeptide azide-functionalized ADC linker intermediate facilitating precise bioorthogonal conjugation in antibody-drug conjugates for stable and site-specific payload attachment. Keywords: ADC linker, peptide linker, azide linker, bioorthogonal chemistry, targeted delivery.

H-(Gly)3-Lys(N3)-OH

Structure of 2250437-45-5

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C12H21N7O5
Molecular Weight
343.34
Storage
Store at 2-8 °C

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
Triglycyl-N-epsilon-azido lysine; H-(Gly)3-Lys(N3); Triglycyl-Ne-azido-L-lysine; Triglycyl-epsilon-azido-L-lysine; (2S)-2-{2-[2-(2-Aminoacetamido)acetamido]acetamido}-6-azidohexanoic acid; H-Gly-Gly-Gly-Lys(N3); H-Gly-Gly-Gly-Nle(N3)-OH; Glycyl-glycyl-glycyl-6-azido-L-norleucine; N6-Diazo-N2-glycylglycylglycyl-L-lysine; H-Gly-Gly-Gly-Lys(N3)-OH
IUPAC Name
(2S)-2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-6-azidohexanoic acid
Canonical SMILES
C(CCN=[N+]=[N-])C[C@@H](C(=O)O)NC(=O)CNC(=O)CNC(=O)CN
InChI
InChI=1S/C12H21N7O5/c13-5-9(20)15-6-10(21)16-7-11(22)18-8(12(23)24)3-1-2-4-17-19-14/h8H,1-7,13H2,(H,15,20)(H,16,21)(H,18,22)(H,23,24)/t8-/m0/s1
InChIKey
OTAJJAGRBJWUDS-QMMMGPOBSA-N
Sequence
Gly-Gly-Gly-Lys(N3)
Storage
Store at 2-8 °C

H-(Gly)3-Lys(N3)-OH, a synthetic peptide featuring an azido group, presents a myriad of potential applications in biochemical research and biotechnology.

Bioorthogonal Chemistry: In the realm of bioorthogonal chemistry, H-(Gly)3-Lys(N3)-OH emerges as a versatile tool for labeling and tracing biomolecules within living systems. The azido group within this peptide engages in click chemistry reactions with alkyne-containing molecules, allowing for precise labeling without disrupting natural biological processes.

Peptide Conjugation: With its azido group, H-(Gly)3-Lys(N3)-OH stands out as a prime candidate for peptide conjugation, offering researchers the opportunity to attach various functional groups or molecules, such as fluorophores or drugs, through click chemistry. This versatility proves invaluable for designing multifunctional peptides tailored for diagnostic and therapeutic applications, showcasing the peptide’s adaptability in diverse settings.

Proteomics: Within the domain of proteomics studies, H-(Gly)3-Lys(N3)-OH finds utility in integrating labels into proteins for mass spectrometry analysis. The azido group enables the selective and efficient attachment of isotopic labels, enhancing the identification and quantification of proteins. This method plays a pivotal role in characterizing proteomes in detail and shedding light on the dynamic expression patterns of proteins.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2-(4-nitrophenyl)carbonate-Fmoc | Norbornene-NHS | beta-Lac-TEG-N3 | N3-TOTA-Suc | Bz-(Me)Tz-NHS | N3Ac-OPhOMe | Boc-Ser(O-propargyl)-OH | (2S)-N3-IsoSer | H-L-Phe(4-NH-Poc)-OH HCl | SCO-PEG2-Maleimide | H-(Gly)3-Lys(N3)-OH
Send Inquiry
Verification code
Inquiry Basket