H-(Gly)3-Lys(N3)-OH - CAS 2250437-45-5

H-(Gly)3-Lys(N3)-OH - CAS 2250437-45-5 Catalog number: BADC-01769

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H-(Gly)3-Lys(N3)-OH is a click chemistry reagent containing an azide group.

Category
ADCs Linker
Product Name
H-(Gly)3-Lys(N3)-OH
CAS
2250437-45-5
Catalog Number
BADC-01769
Molecular Formula
C12H21N7O5
Molecular Weight
343.34

Ordering Information

Catalog Number Size Price Quantity
BADC-01769 -- $-- Inquiry
Description
H-(Gly)3-Lys(N3)-OH is a click chemistry reagent containing an azide group.
IUPAC Name
(2S)-2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-6-azidohexanoic acid
Canonical SMILES
C(CCN=[N+]=[N-])CC(C(=O)O)NC(=O)CNC(=O)CNC(=O)CN
InChI
InChI=1S/C12H21N7O5/c13-5-9(20)15-6-10(21)16-7-11(22)18-8(12(23)24)3-1-2-4-17-19-14/h8H,1-7,13H2,(H,15,20)(H,16,21)(H,18,22)(H,23,24)/t8-/m0/s1
InChIKey
OTAJJAGRBJWUDS-QMMMGPOBSA-N

H-(Gly)3-Lys(N3)-OH, a synthetic peptide featuring an azido group, presents a myriad of potential applications in biochemical research and biotechnology.

Bioorthogonal Chemistry: In the realm of bioorthogonal chemistry, H-(Gly)3-Lys(N3)-OH emerges as a versatile tool for labeling and tracing biomolecules within living systems. The azido group within this peptide engages in click chemistry reactions with alkyne-containing molecules, allowing for precise labeling without disrupting natural biological processes.

Peptide Conjugation: With its azido group, H-(Gly)3-Lys(N3)-OH stands out as a prime candidate for peptide conjugation, offering researchers the opportunity to attach various functional groups or molecules, such as fluorophores or drugs, through click chemistry. This versatility proves invaluable for designing multifunctional peptides tailored for diagnostic and therapeutic applications, showcasing the peptide’s adaptability in diverse settings.

Proteomics: Within the domain of proteomics studies, H-(Gly)3-Lys(N3)-OH finds utility in integrating labels into proteins for mass spectrometry analysis. The azido group enables the selective and efficient attachment of isotopic labels, enhancing the identification and quantification of proteins. This method plays a pivotal role in characterizing proteomes in detail and shedding light on the dynamic expression patterns of proteins.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Fmoc-Lys(IvDde)-OH
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