Name: DGN549-C
Brand: BOC Sciences
Rating: 5 (1 reviews)

IUPAC Name

N'-[(2S)-1-[[(2S)-1-[3-[[(12aS)-8-methoxy-6-oxo-12a,13-dihydroindolo[2,1-c][1,4]benzodiazepin-9-yl]oxymethyl]-5-[[(12aS)-8-methoxy-6-oxo-11,12,12a,13-tetrahydroindolo[2,1-c][1,4]benzodiazepin-9-yl]oxymethyl]anilino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]hexanediamide

Canonical SMILES

CC(C(=O)NC(C)C(=O)NC1=CC(=CC(=C1)COC2=C(C=C3C(=C2)N=CC4CC5=CC=CC=C5N4C3=O)OC)COC6=C(C=C7C(=C6)NCC8CC9=CC=CC=C9N8C7=O)OC)NC(=O)CCCCC(=O)NCCN1C(=O)C=CC1=O

InChI

InChI=1S/C60H61N9O12/c1-34(64-54(71)16-10-9-15-53(70)61-19-20-67-55(72)17-18-56(67)73)57(74)65-35(2)58(75)66-40-22-36(32-80-51-28-45-43(26-49(51)78-3)59(76)68-41(30-62-45)24-38-11-5-7-13-47(38)68)21-37(23-40)33-81-52-29-46-44(27-50(52)79-4)60(77)69-42(31-63-46)25-39-12-6-8-14-48(39)69/h5-8,11-14,17-18,21-23,26-30,34-35,41-42,63H,9-10,15-16,19-20,24-25,31-33H2,1-4H3,(H,61,70)(H,64,71)(H,65,74)(H,66,75)/t34-,35-,41-,42-/m0/s1

Solubility

10 mm in DMSO

Shelf Life

-20°C 3 years powder; -80°C 2 years in solvent

Shipping

Room temperature, or blue ice upon request.

Storage

-20°C

DGN549-C is a versatile compound with multiple applications in the bioscience sector. Here are some key applications of DGN549-C:

Cancer Research: DGN549-C is used in cancer research for its potential to inhibit tumor growth and induce apoptosis in cancerous cells. Researchers utilize DGN549-C to study its mechanism of action and its effects on various cancer cell lines. This aids in discovering new therapeutic strategies and developing anti-cancer drugs.

Drug Discovery: DGN549-C serves as a lead compound in drug discovery programs aimed at developing treatments for various diseases. By assessing the bioactivity and safety profile of DGN549-C, researchers can identify promising drug candidates. This facilitates the development of new medications with enhanced efficacy and reduced side effects.

Pharmacokinetics Studies: DGN549-C is employed in pharmacokinetic studies to evaluate its absorption, distribution, metabolism, and excretion (ADME) properties. Understanding the pharmacokinetics of DGN549-C helps in optimizing its formulation and dosing regimens for therapeutic use. This information is essential for ensuring the safety and effectiveness of the compound in clinical settings.

Biological Pathways Research: DGN549-C is used to probe and manipulate biological pathways related to disease mechanisms and cellular functions. By treating cells or model organisms with DGN549-C, researchers can investigate its impact on specific signaling pathways and gene expression profiles. This contributes to a deeper understanding of disease biology and identification of novel therapeutic targets.