Muscotoxin A - CAS 1653999-47-3
  1. Home
  2. Products
  3. ADCs Cytotoxin
  4. Traditional Cytotoxic Agents
  5. Muscotoxin A

Muscotoxin A - CAS 1653999-47-3 Catalog number: BADC-00817

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death.

Category
ADCs Cytotoxin
Product Name
Muscotoxin A
CAS
1653999-47-3
Catalog Number
BADC-00817
Molecular Formula
C58H90N12O16
Molecular Weight
1211.41
Purity
>98.0%
Target
Cell Membranes

Ordering Information

Catalog Number Size Price Quantity
BADC-00817 -- $-- Inquiry

Featured Recommendations

Recommended Services
ADC Linkers Development Antibody Modification and Conjugation Technologies ADC Analysis and Characterization ADC Linker and Cytotoxin Conjugations ADC Payloads Development ADC Manufacture ADC Development for Targets ADC Development Platform
Other Types of Cytotoxins
Auristatins Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Piericidins Pyrrolobenzodiazepines Traditional Cytotoxic Agents Others
Description
Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death.
IUPAC Name
3-[(6R,13S,19R,22S,25Z,28S,31R,34S,37S)-34-benzyl-19,31-bis[(2S)-butan-2-yl]-25-ethylidene-9-hydroxy-10-(2-hydroxyheptyl)-22,28-bis(hydroxymethyl)-2,5,8,12,18,21,24,27,30,33,36-undecaoxo-1,4,7,11,17,20,23,26,29,32,35-undecazatricyclo[35.3.0.013,17]tetracontan-6-yl]propanamide
Canonical SMILES
O=C(N1CCC[C@]1(C(NC(CC(CCCCC)O)C(O)C(N[C@H](CCC(N)=O)C(NCC(N2CCC[C@]2(C(N[C@H]3CC4=CC=CC=C4)=O)[H])=O)=O)=O)=O)[H])[C@@]([H])([C@H](CC)C)NC([C@H](CO)NC(/C(NC([C@H](CO)NC([C@@]([H])([C@H](CC)C)NC3=O)=O)=O)=C/C)=O)=O
InChI
InChI=1S/C58H90N12O16/c1-7-11-13-20-35(73)28-38-48(76)57(85)62-37(23-24-44(59)74)49(77)60-29-45(75)69-25-16-21-42(69)54(82)64-39(27-34-18-14-12-15-19-34)51(79)67-46(32(5)8-2)56(84)66-40(30-71)52(80)61-36(10-4)50(78)65-41(31-72)53(81)68-47(33(6)9-3)58(86)70-26-17-22-43(70)55(83)63-38/h10,12,14-15,18-19,32-33,35,37-43,46-48,71-73,76H,7-9,11,13,16-17,20-31H2,1-6H3,(H2,59,74)(H,60,77)(H,61,80)(H,62,85)(H,63,83)(H,64,82)(H,65,78)(H,66,84)(H,67,79)(H,68,81)/b36-10-/t32-,33-,35?,37+,38?,39-,40-,41-,42-,43-,46+,47+,48?/m0/s1
InChIKey
WYLYXGBHDIWORI-BSACXQMXSA-N
Solubility
10 mm in DMSO
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -5°C,keep in dry and avoid sunlight.
In Vitro
Muscotoxin A (0-13.2 μM ; 24 hours) is cytotoxic to YAC-1, Sp/2, and HeLa cancer cell lines (LC50) ranged from 9.9 to 13.2 μM, causing membrane damage and influx of calcium ions.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

Related Products

Doxorubicin EP Impurity A (Daunorubicin)
Doxorubicin EP Impurity A (Daunorubicin)
(CAS: 20830-81-3)
DGN549-C
DGN549-C
(CAS: 2058075-34-4)
Daunorubicin hydrochloride
Daunorubicin hydrochloride
(CAS: 23541-50-6)
MC-Val-Cit-PAB-rifabutin
MC-Val-Cit-PAB-rifabutin
(CAS: 2055900-34-8)
Triptolide
Triptolide
(CAS: 38748-32-2)
Paclitaxel
Paclitaxel
(CAS: 33069-62-4)
Historical Records: Muscotoxin A
Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Featured Services
cGMP Grade Products

BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
Site-Specific Conjugation

BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
Linkers for Bioconjugation

BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
ADC Targets
Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket
loading Loading ......
Delete selectedGo to checkout