Catalog Number | Size | Price | Quantity | ||
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BADC-01074 | -- | $-- | Inquiry |
Azido-C2-SS-PEG2-C2-acid is a versatile bifunctional reagent used in various bioconjugation and molecular biology applications. Here are some key uses of Azido-C2-SS-PEG2-C2-acid:
Site-Specific Protein Labeling: Azido-C2-SS-PEG2-C2-acid can be employed for site-specific labeling of proteins with fluorescent dyes, biotin, or other tags. This reagent uses a cleavable disulfide bond to covalently attach the azide group to proteins, allowing for controlled and reversible modifications. This technique is crucial for studying protein localization, interactions, and dynamics.
Drug Delivery Systems: This bifunctional compound can be used to engineer drug delivery systems by conjugating therapeutic agents to carrier molecules. The presence of a PEG (polyethylene glycol) linker provides improved solubility and biocompatibility, enhancing drug efficacy and reducing toxicity. The cleavable disulfide bond allows for controlled release of the drug at the target site, improving precision in treatment.
Biomaterials Engineering: Azido-C2-SS-PEG2-C2-acid can be instrumental in the design and functionalization of biomaterials for tissue engineering and regenerative medicine. By modifying the surface of biomaterials with this reagent, researchers can improve cell adhesion, growth, and differentiation. This provides a means to create scaffolds and other biomaterials that better mimic the natural extracellular matrix.
Click Chemistry Reactions: The azide moiety in Azido-C2-SS-PEG2-C2-acid makes it ideal for use in click chemistry reactions, which are widely used for bioconjugation. These reactions are highly specific and efficient, allowing for the attachment of various functional groups to biomolecules. This application is valuable in creating complex molecular assemblies, biosensors, and diagnostic tools.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.