Name: Azidoethyl-SS-propionic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

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$--

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Synonyms

3-[(2-azidoethyl)disulfanyl]propanoic acid

IUPAC Name

Canonical SMILES

C(CSSCCN=[N+]=[N-])C(=O)O

InChI

InChI=1S/C5H9N3O2S2/c6-8-7-2-4-12-11-3-1-5(9)10/h1-4H2,(H,9,10)

InChIKey

MIOCIBNCOQTVOB-UHFFFAOYSA-N

Solubility

10 mm in DMSO

Appearance

Solid

Shelf Life

0-4°C for short term (days to weeks), or -20°C for long term (months).

Shipping

Room temperature

Storage

Store at -5°C,keep in dry and avoid sunlight.

Form

Solid

Azidoethyl-SS-propionic acid is a versatile compound employed in various biochemical and biomedical applications. Here are some key applications of Azidoethyl-SS-propionic acid:

Bioorthogonal Chemistry: Azidoethyl-SS-propionic acid is commonly used in bioorthogonal chemistry, where it serves as a precursor for click chemistry reactions. This allows for the selective labeling and modification of biomolecules in living systems without interfering with native biochemical processes. Researchers leverage this technique to study protein interactions, track cellular components, and analyze complex biological systems.

Protein Modification: In protein engineering, Azidoethyl-SS-propionic acid is utilized for modifying proteins with specific functional groups. By incorporating the azido group into proteins, scientists can attach various probes, tags, or therapeutic molecules through click chemistry. This approach enhances the functionality and therapeutic potential of protein-based drugs and diagnostic tools.

Drug Delivery Systems: Azidoethyl-SS-propionic acid plays a crucial role in the development of advanced drug delivery systems. It is used to functionalize drug carriers, such as nanoparticles or liposomes, with targeting ligands or therapeutic agents. This ensures precise delivery of drugs to specific cells or tissues, improving efficacy and reducing off-target effects.

Bioconjugation: Azidoethyl-SS-propionic acid is essential for bioconjugation protocols, enabling the attachment of biomolecules to surfaces, polymers, or other biomolecules. This is particularly useful in the development of biosensors, diagnostic assays, and biomaterials. By facilitating the covalent linkage of bioactive molecules, it enhances the performance and stability of these biotechnological tools.