webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

Azidoethyl-SS-propionic acid

  CAS No.: 2228857-32-5   Cat No.: BADC-01086   Purity: >98.0% 4.5  

Azidoethyl-SS-propionic acid is a cleavable disulfide-containing ADC linker with azide functionality, supporting bioorthogonal click chemistry and controlled intracellular payload release.

Azidoethyl-SS-propionic acid

Structure of 2228857-32-5

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C5H9N3O2S2
Molecular Weight
207.27
Shipping
Room temperature
Shipping
Store at -5°C,keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
3-[(2-azidoethyl)disulfanyl]propanoic acid
IUPAC Name
Canonical SMILES
C(CSSCCN=[N+]=[N-])C(=O)O
InChI
InChI=1S/C5H9N3O2S2/c6-8-7-2-4-12-11-3-1-5(9)10/h1-4H2,(H,9,10)
InChIKey
MIOCIBNCOQTVOB-UHFFFAOYSA-N
Solubility
10 mm in DMSO
Appearance
Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature
Storage
Store at -5°C,keep in dry and avoid sunlight.
Form
Solid

Azidoethyl-SS-propionic acid is a versatile compound employed in various biochemical and biomedical applications. Here are some key applications of Azidoethyl-SS-propionic acid:

Bioorthogonal Chemistry: Azidoethyl-SS-propionic acid is commonly used in bioorthogonal chemistry, where it serves as a precursor for click chemistry reactions. This allows for the selective labeling and modification of biomolecules in living systems without interfering with native biochemical processes. Researchers leverage this technique to study protein interactions, track cellular components, and analyze complex biological systems.

Protein Modification: In protein engineering, Azidoethyl-SS-propionic acid is utilized for modifying proteins with specific functional groups. By incorporating the azido group into proteins, scientists can attach various probes, tags, or therapeutic molecules through click chemistry. This approach enhances the functionality and therapeutic potential of protein-based drugs and diagnostic tools.

Drug Delivery Systems: Azidoethyl-SS-propionic acid plays a crucial role in the development of advanced drug delivery systems. It is used to functionalize drug carriers, such as nanoparticles or liposomes, with targeting ligands or therapeutic agents. This ensures precise delivery of drugs to specific cells or tissues, improving efficacy and reducing off-target effects.

Bioconjugation: Azidoethyl-SS-propionic acid is essential for bioconjugation protocols, enabling the attachment of biomolecules to surfaces, polymers, or other biomolecules. This is particularly useful in the development of biosensors, diagnostic assays, and biomaterials. By facilitating the covalent linkage of bioactive molecules, it enhances the performance and stability of these biotechnological tools.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Maytansinoid B | Fmoc-PEG4-NHS ester | t-Boc-N-amido-PEG7-alcohol | m-PEG8-COOH | γ-Amanitin | 5-Maleimidovaleric acid | Boc-NH-ethyl-SS-propionic acid | Fmoc-NH-ethyl-SS-propionic acid | THP-SS-PEG1-Tos | Acid-PEG2-SS-PEG2-acid | Azidoethyl-SS-propionic acid
Send Inquiry
Verification code
Inquiry Basket