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Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride)

  CAS No.: 1416771-72-6   Cat No.: BADC-01662 4.5  

Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride) is a cleavable PEG ADC linker and also a PEG-based PROTAC linker.

Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride)

Structure of 1416771-72-6

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ADC Linker
Molecular Formula
C13H24ClNO9
Molecular Weight
373.78

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Synonyms
3,3'-((2-Amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionic acid hydrochloride
IUPAC Name
3-[2-amino-3-(2-carboxyethoxy)-2-(2-carboxyethoxymethyl)propoxy]propanoic acid;hydrochloride
Canonical SMILES
C(COCC(COCCC(=O)O)(COCCC(=O)O)N)C(=O)O.Cl
InChI
InChI=1S/C13H23NO9.ClH/c14-13(7-21-4-1-10(15)16,8-22-5-2-11(17)18)9-23-6-3-12(19)20;/h1-9,14H2,(H,15,16)(H,17,18)(H,19,20);1H
InChIKey
ACGZZBXQNDTJIA-UHFFFAOYSA-N

Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride) is a compound with diverse applications across bioscience and industry. Here are four key applications of Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride):

Chelation Therapy: Serving as a potent chelating agent, this compound exhibits the remarkable ability to bind to heavy metals, effectively aiding in their removal from the body. Its efficacy is particularly evident in the treatment of heavy metal poisoning instances, such as lead or mercury toxicity. Health professionals administer this chelating agent strategically to prevent the detrimental impacts of heavy metals on the various organ systems, showcasing its vital role in promoting overall well-being.

Water Treatment: Widely harnessed in water treatment applications, Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride) plays a pivotal role in eliminating heavy metal contaminants from water sources. Through its capability to form complexes with dissolved metals, this compound enables the easy filtration or precipitation of toxic elements. This application not only ensures the provision of safe potable water devoid of harmful metal ions but also underscores its commitment to environmental conservation, safeguarding aquatic ecosystems.

Pharmaceutical Formulations: In the realm of pharmaceutical research, this compound emerges as a key player in stabilizing drug formulations, acting as an essential excipient. Its chelating properties come into play by effectively mitigating the degradation of active pharmaceutical ingredients through the binding of trace metal impurities. By safeguarding the efficacy and extending the shelf-life of medications, it establishes a crucial foundation for patient safety and well-being, exemplifying its indispensable role in pharmaceutical sciences.

Cosmetic Applications: The chelating prowess of Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride) extends to the realm of cosmetic products, where it adds significant value. Incorporation of this compound into formulations serves to enhance product stability and combat oxidative damage caused by metal ions. This proactive approach not only ensures the quality and durability of personal care items like creams and lotions but also highlights its pivotal role in preserving the integrity of cosmetic formulations, catering to the evolving needs of consumers.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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