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Amino-Tri-(carboxyethoxymethyl)-methane

  CAS No.: 174362-95-9   Cat No.: BADC-00990   Purity: >98.0% 4.5  

Amino-Tri-(carboxyethoxymethyl)-methane is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Amino-Tri-(carboxyethoxymethyl)-methane

Structure of 174362-95-9

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Category
ADC Linker
Molecular Formula
C13H23NO9
Molecular Weight
337.32
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
Tris{[2-carboxyethoxy]methyl}methylamine; 3,3'-((2-amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionic acid
IUPAC Name
3-[2-amino-3-(2-carboxyethoxy)-2-(2-carboxyethoxymethyl)propoxy]propanoic acid
Canonical SMILES
C(COCC(COCCC(=O)O)(COCCC(=O)O)N)C(=O)O
InChI
InChI=1S/C13H23NO9/c14-13(7-21-4-1-10(15)16,8-22-5-2-11(17)18)9-23-6-3-12(19)20/h1-9,14H2,(H,15,16)(H,17,18)(H,19,20)
InChIKey
PZOSHMSOMAHCEX-UHFFFAOYSA-N
Solubility
10 mm in DMSO
Appearance
Solid
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Form
Solid

Amino-Tri-(carboxyethoxymethyl)-methane, a remarkably versatile chemical compound, finds its applications spanning diverse industries and biomedicine. Here are four key applications elaborated with a high degree of perplexity and burstiness:

Chelating Agent: Within the intricate operations of various industries, Amino-Tri-(carboxyethoxymethyl)-methane emerges as a pivotal chelating agent, showcasing its adeptness at binding and sequestering metal ions. Its significance is particularly pronounced in water treatment, where it plays a crucial role in the elimination of heavy metals and the prevention of scale formation within pipelines and boilers. By stabilizing metal ions, this compound not only enhances the efficiency of industrial processes but also shields equipment from potential damage, ensuring seamless operations and longevity.

Biodegradable Detergents: In the realm of eco-conscious cleaning solutions, Amino-Tri-(carboxyethoxymethyl)-methane stands out as a key ingredient in biodegradable detergents and cleaning agents. Its capacity to chelate metal ions elevates the cleaning efficacy of detergents, enabling the effective removal of stains and grime. This fosters the development of environmentally sustainable cleaning solutions that are gentle on both humanity and aquatic ecosystems.

Biomedical Research: Within the realm of biomedical research, Amino-Tri-(carboxyethoxymethyl)-methane serves as a critical buffer and stabilization agent in numerous biochemical assays and drug formulations. Its role in maintaining the stability of proteins, enzymes, and other biological entities bolsters the reliability of experimental outcomes, thereby advancing pharmaceutical and diagnostic innovations.

Agricultural Biotechnology: Delving into the agricultural domain, Amino-Tri-(carboxyethoxymethyl)-methane emerges as a valuable ally, functioning as a soil conditioner and nutrient transporter. By encapsulating essential micronutrients, it facilitates their gradual and controlled release to plants, enriching the availability and uptake of nutrients. This transformative process culminates in enhanced plant growth, amplified crop yields, and fortified soil vitality, laying the groundwork for sustainable agricultural practices and ensuring the flourishing of our agricultural ecosystems.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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