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Gly-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01063 | -- | $-- | Inquiry |
Gly-PEG3-amine is a versatile chemical reagent widely used in bioconjugation and therapeutic development. Here are some key applications of Gly-PEG3-amine:
Drug Delivery: Gly-PEG3-amine is used to modify drug molecules and enhance their delivery to specific tissues or cells. By conjugating this molecule to therapeutic agents, it improves their solubility, stability, and bioavailability. This is particularly beneficial in the development of targeted drug delivery systems for treating cancer and other diseases.
Protein Labeling: In the field of proteomics and biochemistry, Gly-PEG3-amine is employed to label proteins with various tags for detection, purification, or immobilization. The PEG3 spacer provides sufficient flexibility, reducing steric hindrance and maintaining protein functionality. This facilitates downstream applications such as affinity purification, imaging, and diagnostic assays.
Surface Modification: Gly-PEG3-amine can be used to functionalize surfaces with amine groups, providing a reactive site for further chemical modifications. This application is crucial in developing biosensors, tissue engineering scaffolds, and medical implants. By creating a bio-compatible and functional surface, it enhances the interaction with biological molecules and cells.
Polymer Development: Gly-PEG3-amine is utilized in the synthesis of advanced polymeric materials for biomedical applications. It serves as a building block for creating polymers with controlled architecture and functionalities. These materials are used in developing hydrogels, drug delivery vehicles, and tissue engineering scaffolds, providing tailored properties for specific applications.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
