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TKN87180

  CAS No.: 756487-18-0   Cat No.: BADC-01499 4.5  

TKN87180 is a specialized ADC linker formulated for enhanced stability and site-specific conjugation, supporting improved pharmacokinetics and selective drug release in antibody-drug conjugate therapies.

TKN87180

Structure of 756487-18-0

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Category
ADC Linker
Molecular Formula
C37H49N5O8
Molecular Weight
691.81
Storage
solvent: -80°C 12 months; Powder: -20°C 3 years

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
Mc-Phe-Lys(Boc)-PAB; tert-Butyl ((S)-5-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-phenylpropanamido)-6-((4-(hydroxymethyl)phenyl)amino)-6-oxohexyl)carbamate
IUPAC Name
tert-butyl N-[(5S)-5-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-phenylpropanoyl]amino]-6-[4-(hydroxymethyl)anilino]-6-oxohexyl]carbamate
Canonical SMILES
CC(C)(C)OC(=O)NCCCCC(C(=O)NC1=CC=C(C=C1)CO)NC(=O)C(CC2=CC=CC=C2)NC(=O)CCCCCN3C(=O)C=CC3=O
InChI
InChI=1S/C37H49N5O8/c1-37(2,3)50-36(49)38-22-10-9-14-29(34(47)39-28-18-16-27(25-43)17-19-28)41-35(48)30(24-26-12-6-4-7-13-26)40-31(44)15-8-5-11-23-42-32(45)20-21-33(42)46/h4,6-7,12-13,16-21,29-30,43H,5,8-11,14-15,22-25H2,1-3H3,(H,38,49)(H,39,47)(H,40,44)(H,41,48)/t29-,30-/m0/s1
InChIKey
TUPIPBYBJMCLLM-KYJUHHDHSA-N
Storage
solvent: -80°C 12 months; Powder: -20°C 3 years

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Vc-MMAD | Belantamab mafodotin | MC-PEG2-C2-NHS ester | C2-Amide-C4-NH2 | Taltobulin hydrochloride | N-(2-(2,3-Dimethylphenoxy)ethyl)-4-Formylbenzamide | Methotrexate | Irinotecan EP Impurity E (SN-38) | Acid-C3-SSPy | BA-3011 | TKN87180
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