AcLys-PABC-VC-Aur0101 is a cleavable anti-CXCR4 drug-linker conjugates for ADC. It has potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the cleavable linker AcLys-PABC-VC.
Structure of 1438851-17-2
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Capabilities & Facilities
AcLys-PABC-VC-Aur0101 is a novel drug conjugate designed for targeted cancer therapy. Here are some key applications of AcLys-PABC-VC-Aur0101:
Targeted Chemotherapy: AcLys-PABC-VC-Aur0101 is engineered to deliver cytotoxic agents directly to cancer cells, minimizing damage to healthy tissues. By targeting specific tumor markers, this approach increases the efficacy of chemotherapy while reducing common side effects. This precision in targeting enhances the overall treatment outcomes for patients.
Drug Delivery Systems: The conjugate structure of AcLys-PABC-VC-Aur0101 allows for the incorporation of various therapeutic payloads. Its design can be adapted to carry different drugs, making it a versatile platform for treating various types of cancers. This adaptability is crucial for personalized medicine, where treatments are tailored to individual patient's tumor profiles.
Combination Therapy: AcLys-PABC-VC-Aur0101 can be used in combination with other therapeutic agents to enhance anti-cancer efficacy. By synergizing with other drugs, it can overcome resistance mechanisms and improve treatment responses. This multi-faceted approach is essential for tackling aggressive and treatment-resistant cancers.
Tumor Imaging: The molecular structure of AcLys-PABC-VC-Aur0101 can be modified to include imaging agents, enabling its use in diagnostic imaging. This allows clinicians to visualize tumor localization and drug distribution in real-time. Such imaging capabilities are beneficial for monitoring treatment progression and optimizing therapeutic strategies.
Catalog | Product Name | CAS | Inquiry |
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BADC-01741 | AcLys-PABC-VC-Aur0101 intermediate-1 | 1609108-48-6 |
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