Name: AcLys-PABC-VC-Aur0101 intermediate-1
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Synonyms

N2-acetyl-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysyl-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-omithinamide

IUPAC Name

9H-fluoren-9-ylmethyl N-[(5S)-5-acetamido-6-[[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-6-oxohexyl]carbamate

Canonical SMILES

CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)C(CCCCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)NC(=O)C

InChI

InChI=1S/C41H53N7O8/c1-25(2)36(39(53)47-35(16-10-22-43-40(42)54)37(51)46-28-19-17-27(23-49)18-20-28)48-38(52)34(45-26(3)50)15-8-9-21-44-41(55)56-24-33-31-13-6-4-11-29(31)30-12-5-7-14-32(30)33/h4-7,11-14,17-20,25,33-36,49H,8-10,15-16,21-24H2,1-3H3,(H,44,55)(H,45,50)(H,46,51)(H,47,53)(H,48,52)(H3,42,43,54)/t34-,35-,36-/m0/s1

InChIKey

FUKMTJHGXXYHHK-KVBYWJEESA-N

AcLys-PABC-VC-Aur0101 intermediate-1 plays a pivotal role in the synthesis of drug conjugates, particularly antibody-drug conjugates (ADCs). Explore its diverse applications with a touch of high perplexity and burstiness:

Drug Development: Fueling the frontier of targeted cancer therapies, AcLys-PABC-VC-Aur0101 intermediate-1 acts as the linchpin in ADC creation. By linking antibodies to cytotoxic drugs, it orchestrates precise drug delivery to cancer cells, minimizing collateral damage and heightening therapeutic efficacy.

Cancer Research: In the realm of oncology, this compound stands as a cornerstone for probing the effectiveness and safety of novel anticancer agents. Leveraging AcLys-PABC-VC-Aur0101 intermediate-1, researchers sculpt experimental models, unraveling drug behaviors and mechanisms in preclinical settings, enriching our insights into ADC functionality.

Bioconjugation Studies: Amid the tapestry of bioconjugation, AcLys-PABC-VC-Aur0101 intermediate-1 emerges as a catalyzing force for innovation. Scientists wield this compound to forge new pathways of biomolecule linkage, unveiling avant-garde conjugation techniques with vast implications in biotechnological and pharmaceutical arenas, ushering in a new era of drug delivery systems and diagnostic modalities.

Pharmaceutical Manufacturing: At the core of ADC production lies the indispensable role of AcLys-PABC-VC-Aur0101 intermediate-1. Serving as a linchpin in large-scale synthesis, this compound ensures the uniformity and resilience of the final product, upholding stringent quality benchmarks for clinical application, underpinning the foundation of robust ADC manufacturing processes.