ADCs Cytotoxin
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ADCs Cytotoxin

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Catalog Product Name CAS Number
BADC-00814 DC44SMe 1354787-76-0
DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC) for the targeted treatment of cancer.. Inquiry
BADC-00790 Mithramycin A 18378-89-7
Mimosamycin is a glycoside antibiotic produced by Str. argillaceus, Str. plicatus and Str. tanashiensis. It has anti-Gram-positive bacteria and mycobacterial activity. It can inhibit HeLa cells. Inquiry
BADC-00797 Distamycin A 636-47-5
It is produced by the strain of Streptomyces distallicus NCIB 8936. It has the activity against gram-positive bacterium, mycobacterium, dermatophyte and Trichophyte. It has inhibitory effects on solid tumors such as Epstein-Barr ascites carcinoma, sarcoma 180, Walker 258, oberling-Guerin osteoma, and also inhibits vaccinosis virus, herpes simplex virus, adenovirus, and mouse hepatitis virus in cell culture. Inquiry
BADC-00576 (+)-CBI-CDPI2 128300-15-2
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. It is also a DNA alkylating agent that acts as an antibody drug conjugate (ADC) toxin. Inquiry
BADC-00778 Pladienolide B 445493-23-2
a potent pre-mRNA splicing inhibitor. Pladienolide B has shown strong inhibitory effect against activity and growth of various cell lines via targeting SF3b. Inquiry
BADC-00089 Calicheamicin 108212-75-5
Calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, The main component is calicheamicin γ1. It has strong anti-Gram-positive bacteria activity and anti-tumor effect. Inquiry
BADC-00086 Mertansine 139504-50-0
Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. Inquiry
BADC-01392 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methoxy-, (4S)- 19685-10-0
Possess high anti-cancer properties. Inquiry
BADC-00087 Maytansinoid DM4 799840-96-3
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00186 Adaphotris
Inhibitor of Ca2+/2H+-exchange system in liver mitochondria. , synthetic. Inquiry
BADC-00243 14-Benzoyltalatisamine Perchlorate
A selective blocker of the delayed rectifier K+ channel found in virtual screening Inquiry
BADC-00257 Dihydroatisine HCl
An antiarrhythmic of 1-st and 1Y classes and a blocker of TTX sensitive Na+ channels, Ca++ antagonist diterpene alkaloid from Delphinium staphisagria. Inquiry
BADC-00258 Donaxine iodomethylate 5457-31-8
Donaxine is a naturally occurring indole alkaloid present in several plant species; Analeptic of CNS, tocolytic indole alkaloid Derived from the basic alkaloid Donaxine (gramine) extracted from Arundo donax (Gramineae fam.) Inquiry
BADC-00263 FSP-1
Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, identifies an inflammatory subpopulation of macrophages in the liver. Inquiry
BADC-00264 FSP-2
Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised. Inquiry
BADC-00265 FSP-3
Anticoagulant: irreversible inhibits serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised. Inquiry
BADC-00273 Imperatoxin-Inhibitor
Imperatoxin is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. an inhibitor of Ca2+-release channels from sarcoplasmic reticulum. Inquiry
BADC-00275 Imperialine iodomethylate
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family) Inquiry
BADC-00276 3-alpha-iodo-Imperialine
A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant Petilium eduardi and P.raddeanae (Liliaceae fam.) Inquiry
BADC-00277 3-beta-iodo-Imperialine
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A selective M2 muscarinic receptor antagonist. Inquiry
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