Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00017 | DM4-SMCC | 1228105-52-9 |
| DM4 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. | Inquiry | |
| BADC-00026 | Mc-MMAD | 1401963-15-2 |
| Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. | Inquiry | |
| BADC-00027 | INNO-206 | 1361644-26-9 |
| INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. | Inquiry | |
| BADC-00028 | DOXO-EMCH | 151038-96-9 |
| DOXO-EMCH is an albumin-binding prodrug of doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. | Inquiry | |
| BADC-00032 | PF-06380101 | 1436391-86-4 |
| PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs. | Inquiry | |
| BADC-00034 | Taltobulin | 228266-40-8 |
| Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. HTI-286 was a potent inhibitor of proliferation (mean IC50 = 2.5 ± 2.1 nm in 18 human tumor cell lines) and had substantially less interaction with multidrug resistance protein (P-glycoprotein) than currently used antimicrotubule agents, including paclitaxel, docetaxel, vinorelbine, or vinblastine. | Inquiry | |
| BADC-00035 | Taltobulin trifluoroacetate | 228266-41-9 |
| Taltobulin trifluoroacetate is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis. | Inquiry | |
| BADC-00039 | Daunorubicin EP Impurity D (Doxorubicin) | 23214-92-8 |
| Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | Inquiry | |
| BADC-00042 | Doxorubicin EP Impurity A (Daunorubicin) | 20830-81-3 |
| Daunomycin is an anthracycline antibiotic produced by Streptomyces peucetius. The mechanism of action is the same as that of doxorubicin, which is inserted into DNA and inhibits RNA and DNA synthesis. It is mainly used for the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. It has anti-gram-positive bacteria, negative bacteria and tumor activity. | Inquiry | |
| BADC-00043 | Daun02 | 290304-24-4 |
| Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction. | Inquiry | |
| BADC-00081 | Ungerine Nitrate | |
| Alkaloid , from plants of the Ungernia genus, Amaryllidaceae. | Inquiry | |
| BADC-00087 | Maytansinoid DM4 | 799840-96-3 |
| DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00129 | Pentazolone hydrochloride | 21314-60-3 |
| Synthetic, an inhibitor of monoamine oxydase.Enhances the toxicity of the Phenamine group and of Tryptamine. | Inquiry | |
| BADC-00179 | Colcemide | 477-30-5 |
| An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L. | Inquiry | |
| BADC-00186 | Adaphotris | |
| Inhibitor of Ca2+/2H+-exchange system in liver mitochondria. , synthetic. | Inquiry | |
| BADC-00190 | 7-Xylosyl-10-deacetyltaxol | 90332-63-1 |
| 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility. | Inquiry | |
| BADC-00223 | Duocarmycin A | 118292-34-5 |
| It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has strong antibacterial and antitumor activity. It can inhibit gram-positive bacteria such as Staphylococcus aureus and Streptococcus faecalis (MIC is less than 0.01 μg/mL), it can also inhibit klebsiella pneumoniae (MIC is 0.032 μg/mL), other bacteria and yeast (MIC is 1-10 μg/mL). | Inquiry | |
| BADC-00243 | 14-Benzoyltalatisamine Perchlorate | |
| A selective blocker of the delayed rectifier K+ channel found in virtual screening | Inquiry | |
| BADC-00257 | Dihydroatisine HCl | |
| An antiarrhythmic of 1-st and 1Y classes and a blocker of TTX sensitive Na+ channels, Ca++ antagonist diterpene alkaloid from Delphinium staphisagria. | Inquiry | |
| BADC-00258 | Donaxine iodomethylate | 5457-31-8 |
| Donaxine is a naturally occurring indole alkaloid present in several plant species; Analeptic of CNS, tocolytic indole alkaloid Derived from the basic alkaloid Donaxine (gramine) extracted from Arundo donax (Gramineae fam.) | Inquiry |
