Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-01400 | Seco-DUBA | 1227961-59-2 |
| seco-DUBA hydrochloride is a cell-permeable pro-drug that is cleaved into the active toxin (DUBA) in intracellular lysosomes by proteases, after internalization. The payload then alkylates the DNA, causing DNA damage and cell death. | Inquiry | |
| BADC-00001 | CBT-161 | |
| CBT-161 is an ADC that STI-A0602, the monoclonal antibody targeting c-Met, links tubulin inhibitors or DNA damaging agents via C-lock. Preclinical study showed that CBT-161 significantly inhibited tumor growth. | Inquiry | |
| BADC-00015 | MC-Val-Ala-PBD | 1342820-51-2 |
| MC-Val-Ala-PBD is a protective group conjugated PBD, PBD bind in the minor groove of DNA. | Inquiry | |
| BADC-00017 | DM4-SMCC | 1228105-52-9 |
| DM4 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. | Inquiry | |
| BADC-00026 | Mc-MMAD | 1401963-15-2 |
| Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. | Inquiry | |
| BADC-00027 | INNO-206 | 1361644-26-9 |
| INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. | Inquiry | |
| BADC-00028 | DOXO-EMCH | 151038-96-9 |
| DOXO-EMCH is an albumin-binding prodrug of doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. | Inquiry | |
| BADC-00032 | PF-06380101 | 1436391-86-4 |
| PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs. | Inquiry | |
| BADC-00034 | Taltobulin | 228266-40-8 |
| Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. HTI-286 was a potent inhibitor of proliferation (mean IC50 = 2.5 ± 2.1 nm in 18 human tumor cell lines) and had substantially less interaction with multidrug resistance protein (P-glycoprotein) than currently used antimicrotubule agents, including paclitaxel, docetaxel, vinorelbine, or vinblastine. | Inquiry | |
| BADC-00035 | Taltobulin trifluoroacetate | 228266-41-9 |
| Taltobulin trifluoroacetate is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis. | Inquiry | |
| BADC-00039 | Doxorubicin | 23214-92-8 |
| Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | Inquiry | |
| BADC-00043 | Daun02 | 290304-24-4 |
| Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction. | Inquiry | |
| BADC-00081 | Ungerine Nitrate | |
| Alkaloid , from plants of the Ungernia genus, Amaryllidaceae. | Inquiry | |
| BADC-00087 | Maytansinoid DM4 | 799840-96-3 |
| DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00129 | Pentazolone hydrochloride | 21314-60-3 |
| Synthetic, an inhibitor of monoamine oxydase.Enhances the toxicity of the Phenamine group and of Tryptamine. | Inquiry | |
| BADC-00179 | Colcemide | 477-30-5 |
| An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L. | Inquiry | |
| BADC-00186 | Adaphotris | |
| Inhibitor of Ca2+/2H+-exchange system in liver mitochondria. , synthetic. | Inquiry | |
| BADC-00190 | 7-Xylosyl-10-deacetyltaxol | 90332-63-1 |
| 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility. | Inquiry | |
| BADC-00223 | Duocarmycin A | 118292-34-5 |
| It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has strong antibacterial and antitumor activity. It can inhibit gram-positive bacteria such as Staphylococcus aureus and Streptococcus faecalis (MIC is less than 0.01 μg/mL), it can also inhibit klebsiella pneumoniae (MIC is 0.032 μg/mL), other bacteria and yeast (MIC is 1-10 μg/mL). | Inquiry | |
| BADC-00243 | 14-Benzoyltalatisamine Perchlorate | |
| A selective blocker of the delayed rectifier K+ channel found in virtual screening | Inquiry |
