Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00190 | 7-Xylosyl-10-deacetyltaxol | 90332-63-1 |
| 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility. | Inquiry | |
| BADC-00042 | Doxorubicin EP Impurity A (Daunorubicin) | 20830-81-3 |
| Daunomycin is an anthracycline antibiotic produced by Streptomyces peucetius. The mechanism of action is the same as that of doxorubicin, which is inserted into DNA and inhibits RNA and DNA synthesis. It is mainly used for the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. It has anti-gram-positive bacteria, negative bacteria and tumor activity. | Inquiry | |
| BADC-00798 | Actinomycin D | 50-76-0 |
| Actinomycin D is a chromopeptide antineoplastic antibiotic that exhibits high antibacterial and antitumor activity. Actinomycin D binds to single- and double-stranded DNA and subsequent inhibition of RNA and protein synthesis. | Inquiry | |
| BADC-00801 | Epirubicin | 56420-45-2 |
| Epirubicin, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. It is clinically active against a broad range of tumor types, including breast cancer, malignant lymphomas, soft tissue sarcomas, lung cancer, pleural mesothelioma, gastrointestinal cancer, head and neck cancer, ovarian cancer, prostatic carcinoma, transitional bladder carcinoma and so on. | Inquiry | |
| BADC-00253 | Luteolin 7-O-glucoside | 5373-11-5 |
| Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin. | Inquiry | |
| BADC-00001 | CBT-161 | |
| CBT-161 is an ADC that STI-A0602, the monoclonal antibody targeting c-Met, links tubulin inhibitors or DNA damaging agents via C-lock. Preclinical study showed that CBT-161 significantly inhibited tumor growth. | Inquiry | |
| BADC-00817 | Muscotoxin A | 1653999-47-3 |
| Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death. | Inquiry | |
| BADC-00818 | Vipivotide tetraxetan | 1702967-37-0 |
| Vipivotide tetraxetan is a high potent inhibitor of prostate-specific membrane antigen (PSMA)(Ki of 0.37 nM). | Inquiry | |
| BADC-00838 | 17-AEP-GA | 75747-23-8 |
| 17-AEP-GA, an ADC toxin and HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. | Inquiry | |
| BADC-00852 | Mc-Dexamethasone | 1618096-56-2 |
| Mc-Dexamethasone is a drug-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasone (HY-14648) conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist. | Inquiry | |
| BADC-00858 | MC-Val-Cit-PAB-rifabutin | 2055900-34-8 |
| MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate for ADC with potent antitumor activity by using rifabutin (an DNA-dependent RNA polymerase inhibitor), linked via the ADC linker MC-Val-Cit-PAB. | Inquiry | |
| BADC-00859 | DGN549-C | 2058075-34-4 |
| DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
| BADC-00036 | Triptolide | 38748-32-2 |
| Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It has immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is an NF-κB activation inhibitor. | Inquiry | |
| BADC-00809 | Mytoxin B | 105049-15-8 |
| Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002. Mytoxin B induces cell apoptosis via PI3K/Akt pathway. An ADC cytotoxin. | Inquiry | |
| BADC-00811 | Duocarmycin DM free base | 1116745-06-2 |
| Duocarmycin DM free base is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. | Inquiry | |
| BADC-00328 | Topotecan | 123948-87-8 |
| Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. | Inquiry | |
| BADC-00330 | Irofulven | 158440-71-2 |
| Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle. | Inquiry | |
| BADC-00800 | Exatecan Mesylate | 169869-90-3 |
| Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. | Inquiry | |
| BADC-00266 | Galantamine hydrobromide | 1953-04-4 |
| Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. | Inquiry | |
| BADC-00039 | Daunorubicin EP Impurity D (Doxorubicin) | 23214-92-8 |
| Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | Inquiry |
