ADCs Cytotoxin
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ADCs Cytotoxin

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Catalog Product Name CAS Number
BADC-00797 Distamycin A 636-47-5
It is produced by the strain of Streptomyces distallicus NCIB 8936. It has the activity against gram-positive bacterium, mycobacterium, dermatophyte and Trichophyte. It has inhibitory effects on solid tumors such as Epstein-Barr ascites carcinoma, sarcoma 180, Walker 258, oberling-Guerin osteoma, and also inhibits vaccinosis virus, herpes simplex virus, adenovirus, and mouse hepatitis virus in cell culture. Inquiry
BADC-00799 Streptonigrin 3930-19-6
Bruneomycin is a benzoquinone antibiotic produced by Auiw-myces albus van bruneomycini and Act. echinatus. It has anti-gram-positive bacteria, negative bacteria, and mycobacterial activity. It has inhibitory effect on lymphosarcoma Lio-1, lymphocytic leukemia NK/L1 and L-5178, Ehrlich ascites carcinoma, sarcoma-180, and has inhibitory effect on sarcoma-37 invalid. Inquiry
BADC-00801 Epirubicin 56420-45-2
Epirubicin, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. It is clinically active against a broad range of tumor types, including breast cancer, malignant lymphomas, soft tissue sarcomas, lung cancer, pleural mesothelioma, gastrointestinal cancer, head and neck cancer, ovarian cancer, prostatic carcinoma, transitional bladder carcinoma and so on. Inquiry
BADC-00809 Mytoxin B 105049-15-8
Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002. Mytoxin B induces cell apoptosis via PI3K/Akt pathway. An ADC cytotoxin. Inquiry
BADC-00811 Duocarmycin DM free base 1116745-06-2
Duocarmycin DM free base is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Inquiry
BADC-00814 DC44SMe 1354787-76-0
DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC) for the targeted treatment of cancer.. Inquiry
BADC-00817 Muscotoxin A 1653999-47-3
Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death. Inquiry
BADC-00818 Vipivotide tetraxetan 1702967-37-0
Vipivotide tetraxetan is a high potent inhibitor of prostate-specific membrane antigen (PSMA)(Ki of 0.37 nM). Inquiry
BADC-00820 C-11 2007965-97-9
C-11 is a tubulin inhibitor and acts as an ADC cytotoxin. It displays cytotoxicity for carcinoma cell lines. Inquiry
BADC-00822 γ-Amanitin 21150-23-2
γ-Amanitin is an ADC cytotoxin isolated from mushrooms. γ-Amanitin inhibits RNA polymerase II and disrupts mRNA synthesis. γ-Amanitin has similar effects to α-Amanitin and β-Amanitin. Inquiry
BADC-00823 ε-Amanitin 21705-02-2
ε-Amanitin, a cyclic peptide isolated from a variety of mushroom species, potently binds to and inhibits the activity of RNA polymerase II. Inquiry
BADC-00824 Luisol A 225110-59-8
Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, anthraquinone antibiotic analog, is an ADC Cytotoxin. Inquiry
BADC-00826 Aniline-MPB-amino-C3-PBD 2412923-79-4
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent. Inquiry
BADC-00827 Py-MPB-amino-C3-PBD 2412924-07-1
Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group, with antimicrobial activity. Inquiry
BADC-00829 Diacetyl Agrochelin 247115-75-9
Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines. Inquiry
BADC-00830 17-GMB-APA-GA 256337-10-7
17-GMB-APA-GA, an ADC cytotoxin, is a potent HSP90 inhibitor used to study latent T. gondii infection. Inquiry
BADC-00831 Telomestatin 265114-54-3
Telomostatin, originally isolated from the bacteria Streptomyces anulatus, is a potent and specific telomerase inhibitor that acts only on human telomere sequences and does not affect DNA polymerases or reverse transcriptases. Telomostatin induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region. Inquiry
BADC-00835 DC4SMe 615538-47-1
DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC) for targeted therapy of tumors. Inquiry
BADC-00836 DC4 615538-48-2
DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors. Inquiry
BADC-00838 17-AEP-GA 75747-23-8
17-AEP-GA, an ADC toxin and HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Inquiry
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