Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00721 | Tubulysin IM-3 | |
| Tubulysin IM-3 can be used in the synthesis of Tubulysin anologs. Tubulysin anologs is a class of microtubule-disrupting agents and can be used as cytotoxins in antibody-drug-conjugation (ADC). | Inquiry | |
| BADC-00722 | Duocarmycin DM | |
| Duocarmycin DM is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. | Inquiry | |
| BADC-00738 | MA-PEG4-VA-PBD | 1342820-68-1 |
| MA-PEG4-VA-PBD is a drug-linker conjugate for ADC by using PBD (Pyrrolobenzodiazepine dimers, a potent antitumor antibiotic), linked via MA-PEG4-VA. | Inquiry | |
| BADC-00751 | DBCO-PEG4-MMAF | 2360411-65-8 |
| DBCO-PEG4-MMAF is a drug-linker conjugate for ADC by using Monomethylauristatin F (MMAF,a potent tubulin polymerization inhibitor), linked via DBCO-PEG4. | Inquiry | |
| BADC-00771 | Thailanstatin B | |
| a Pre-mRNA splicing inhibitor. Thailanstatin B is used as a cytotoxin for ADCs. | Inquiry | |
| BADC-00772 | Thailanstatin C | |
| a Pre-mRNA splicing inhibitor. Thailanstatin C is used as a cytotoxin for ADCs. | Inquiry | |
| BADC-00773 | Thailanstatin D | |
| a Pre-mRNA splicing inhibitor. The direct precursor of Thailanstatin A. Thailanstatin D is used as a cytotoxin for ADCs. | Inquiry | |
| BADC-00774 | Fr901463 | |
| a potent cell cycle inhibitor. Fr901463 exhibited potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. | Inquiry | |
| BADC-00777 | Meayamycin | |
| a potent pre-mRNA splicing inhibitor. Meayamycin modulates or inhibits splicing by targeting SF3B1. | Inquiry | |
| BADC-00779 | Pladienolide D | |
| a potent pre-mRNA splicing inhibitor. Pladienolide D has shown strong antitumor activity via targeting SF3b. | Inquiry | |
| BADC-00780 | Spliceostatin A | 391611-36-2 |
| Spliceostatin A is a potent inhibitor of in vitro and in vivo pre-mRNA splicing. It was shown to inhibit splicing and to interact with an essential component of the spliceosome, SF3b. Spliceostatin A is an inhibitor of RNA synthesis with excellent anticancer activity against a variety of human cancer cell lines. Spliceostatin A inhibits mitotic clone expansion and adipogenesis. | Inquiry | |
| BADC-00781 | Spliceostatin B | |
| a potent pre-mRNA splicing inhibitor. Spliceostatin B, an analog of FR901464, shows a weaker cytotoxic effect in cancer cells than FR901464. | Inquiry | |
| BADC-00782 | Spliceostatin C | |
| a potent pre-mRNA splicing inhibitor. Spliceostatin C is an analog of the natural product FR901464 and has shown a potent inhibit activity of eukaryotic RNA splicing via binding to SF3b. | Inquiry | |
| BADC-00783 | Sudemycin C | |
| a potent pre-mRNA splicing inhibitor. Sudemycin C has a potent inhibit activity of eukaryotic RNA splicing via binding to SF3b. | Inquiry | |
| BADC-00785 | Sudemycin E | 1197054-49-1 |
| a potent pre-mRNA splicing inhibitor. Sudemycin E is an analog of the natural product FR901464 and show a potent inhibit activity of cancer cell lines. | Inquiry | |
| BADC-00786 | Sudemycin E0 | |
| a potent pre-mRNA splicing inhibitor. Sudemycin E0 is an analog of the natural product FR901464 and shows a potent inhibit activity of cancer cell lines. | Inquiry | |
| BADC-00787 | Sudemycin F1 | |
| a potent pre-mRNA splicing inhibitor. Sudemycin F1 is an analog of the natural product FR901464 and shows a potent inhibit activity of cancer cell lines. | Inquiry | |
| BADC-00793 | PDM3 | |
| 20-O-Deme-thylansamitocin P-3 (PDM3),an ansamacrolide and maytansine analogue, has a greater antitumor activities against P388 and L 1210 than AP3. | Inquiry | |
| BADC-00794 | Esperamicin | |
| Esperamicinis an antitumor antibiotics, which combines the structural features of the anthracyclines and the enediynes. Esperamicinis are extremely toxic DNA splicing compounds and exhibits highly potent antitumor activity. | Inquiry | |
| BADC-00795 | Anthramcyin | |
| Anthramycin is a class of Pyrrolobenzodiazepines (PBDs)that shows antibacterial and potent antitumor activity. Anthramycin works by selectively inhibiting the synthesis of RNA and DNA of carcinoma cells. | Inquiry |
