Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-01366 | Gly-Cyclopropane-Exatecan | 2414254-49-0 |
| Gly-Cyclopropane-Exatecan is a derivative of Exatecan. Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity and has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others. | Inquiry | |
| BADC-01367 | Seco-DUBA hydrochloride | 1795733-93-5 |
| Seco-DUBA hydrochloride is the toxin molecule of the ADC drug SYD985. | Inquiry | |
| BADC-01368 | NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT | 2857037-69-3 |
| NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a toxin payload in antibody drug conjugates that can inhibit topoisomerase I, and has good ADC activity in vivo and in vitro. | Inquiry | |
| BADC-01369 | Hemiasterlin | 157207-90-4 |
| Hemiasterlin, a highly cytotoxic marine natural product, is used in a targeted therapeutic which was demonstrated by incorporation as a payload in an antibody-drug conjugate (ADC). It acts by inducing mitotic arrest and abnormal spindle formation. | Inquiry | |
| BADC-01370 | Azonafide-PEABA | |
| Azonafide-PEABA is a cytotoxic drug. | Inquiry | |
| BADC-01372 | INX-SM-6 | 2734878-16-9 |
| INX-SM-6 is a cytotoxic that can be used for targeted anti-inflammatory agent. INX-SM-6 inhibits human PBMCS producting LPS-induced IL-1β. | Inquiry | |
| BADC-01373 | Corixetan | 1952359-26-0 |
| Corixetan is an efficient chelator with thorium. | Inquiry | |
| BADC-01374 | Hemiasterlin derivative-1 | 1887046-60-7 |
| Hemiasterlin derivative-1 is a derivative of hemiasterlin. Hemiasterlin inhibits cell growth by depolymerizing existing microtubules and inhibiting microtubule assembly. | Inquiry | |
| BADC-01375 | CC-885-CH2-PEG1-NH-CH3 | 2722698-03-3 |
| CC-885-CH2-PEG1-NH-CH3 is a neoDegrader used in Antibody neoDegrader Conjugate (AnDC). | Inquiry | |
| BADC-01376 | INX-SM-56 | 2734878-18-1 |
| INX-SM-56 is an ADC cytotoxin used for the synthesis of anti-VISTA ADC. | Inquiry | |
| BADC-01405 | Exatecan hydrochloride | 144008-87-7 |
| Exatecan hydrochloride is the salt of Exatecan, which is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan is an inhibitor of DNA topoisomerase I. | Inquiry | |
| BADC-01617 | ADC toxin 1 | 723340-57-6 |
| ADC toxin 1 is an ADC cytotoxin with anti-cancer activities. ADC toxin 1 is against HCT-116 and PSN1 cells growth with both IC50 values of 0.86 µM. | Inquiry | |
| BADC-01436 | DC44 | 1354787-77-1 |
| DC44, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44 can be used for the targeted treatment of cancer. | Inquiry | |
| BADC-01437 | Tolytoxin | 127999-44-4 |
| Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its polymerization. Tolytoxin has cytotoxic effects in cancer cells. | Inquiry | |
| BADC-01440 | Dxd-D5 | |
| Dxd-D5 (Exatecan-D5 derivative for ADC) is a tritiated version of Dxd. Dxd is a potent DNA topoisomerase I inhibitor with IC50 of 0.31 μM, which can be used as a payload of an antibody drug-conjugated ADC (DS-8201a) targeting HER2. | Inquiry | |
| BADC-01443 | 7-Aminomethyl-10-methyl-11-fluoro camptothecin | 2378616-23-8 |
| 7-Aminomethyl-10-methyl-11-fluoro camptothecin is a toxin molecule of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158, compound 21a), which can be used to synthesize camptothecin antibody Drug Conjugates (ADCs). | Inquiry | |
| BADC-01444 | MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin | 2414594-29-7 |
| MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a) is a camptothecin payload that can be conjugated with a monoclonal antibody (mAb) to synthesize a camptothecin antibody drug conjugate ( ADC). | Inquiry | |
| BADC-01458 | SuO-Val-Cit-PAB-MMAE | |
| SuO-Val-Cit-PAB-MMAE is part of an antibody drug conjugate (drug-linker conjugate for ADC). Consists of the peptide SuO-Val-Cit-PAB linked to the antimitotic agent MMAE, a tubulin inhibitor. | Inquiry | |
| BADC-01459 | MC-betaglucuronide-MMAE-1 | 1703778-92-0 |
| MC-betaglucuronide-MMAE-1 is part of an antibody-drug conjugate consisting of tubulin polymerization inhibitor MMAE and degradable ADC linker MC-betaglucuronide. | Inquiry | |
| BADC-01460 | DBM-MMAF | 1810001-93-4 |
| DBM-MMAF is composed of linker DBM and toxic molecule MMAF, which can be used to prepare antibody-conjugated drugs. | Inquiry |
