Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-01447 | Paclitaxel D5 | 1129540-33-5 |
| Paclitaxel D5 is deuterium-labeled paclitaxel. Paclitaxel is a natural antineoplastic agent that stabilizes tubulin aggregation. | Inquiry | |
| BADC-00820 | C-11 | 2007965-97-9 |
| C-11 is a tubulin inhibitor and acts as an ADC cytotoxin. It displays cytotoxicity for carcinoma cell lines. | Inquiry | |
| BADC-00822 | γ-Amanitin | 21150-23-2 |
| γ-Amanitin is an ADC cytotoxin isolated from mushrooms. γ-Amanitin inhibits RNA polymerase II and disrupts mRNA synthesis. γ-Amanitin has similar effects to α-Amanitin and β-Amanitin. | Inquiry | |
| BADC-00823 | ε-Amanitin | 21705-02-2 |
| ε-Amanitin, a cyclic peptide isolated from a variety of mushroom species, potently binds to and inhibits the activity of RNA polymerase II. | Inquiry | |
| BADC-00824 | Luisol A | 225110-59-8 |
| Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, anthraquinone antibiotic analog, is an ADC Cytotoxin. | Inquiry | |
| BADC-00826 | Aniline-MPB-amino-C3-PBD | 2412923-79-4 |
| Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent. | Inquiry | |
| BADC-00827 | Py-MPB-amino-C3-PBD | 2412924-07-1 |
| Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group, with antimicrobial activity. | Inquiry | |
| BADC-00829 | Diacetyl Agrochelin | 247115-75-9 |
| Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines. | Inquiry | |
| BADC-00830 | 17-GMB-APA-GA | 256337-10-7 |
| 17-GMB-APA-GA, an ADC cytotoxin, is a potent HSP90 inhibitor used to study latent T. gondii infection. | Inquiry | |
| BADC-00831 | Telomestatin | 265114-54-3 |
| Telomostatin, originally isolated from the bacteria Streptomyces anulatus, is a potent and specific telomerase inhibitor that acts only on human telomere sequences and does not affect DNA polymerases or reverse transcriptases. Telomostatin induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region. | Inquiry | |
| BADC-00835 | DC4SMe | 615538-47-1 |
| DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC) for targeted therapy of tumors. | Inquiry | |
| BADC-00836 | DC4 | 615538-48-2 |
| DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors. | Inquiry | |
| BADC-00843 | D8-MMAD | |
| D8-MMAD is a deuterated form of MMAD, which is a microtubule disrupting agent. | Inquiry | |
| BADC-00844 | D8-MMAF hydrochloride | |
| D8-MMAF hydrochloride is a deuterated form of MMAF hydrochloride, which is a microtubule disrupting agent. | Inquiry | |
| BADC-00845 | Isofistularin-3 | |
| Isofistularin-3 is a direct, DNA-competitive DNMT1 inhibitor, with an IC50 of 13.5 μM. Isofistularin-3, as a DNA demethylating agent, induces cell cycle arrest and sensitization to TRAIL in cancer cells. Isofistularin-3 can be used as an ADC cytotoxin. | Inquiry | |
| BADC-00847 | CL2-SN-38 | 1036969-20-6 |
| CL2-SN-38 is a cleavable linker-based antibody-drug conjugate (ADC) containing the topoisomerase I inhibitor SN-38 and a maleimidocaproyl linker. | Inquiry | |
| BADC-00848 | MC-DM1 | 1375089-56-7 |
| MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC). | Inquiry | |
| BADC-00851 | Tesirine | 1595275-62-9 |
| Tesirine (SG3249) is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication. | Inquiry | |
| BADC-00853 | MC-VC-PABC-DNA31 | 1639352-03-6 |
| MC-VC-PABC-DNA31 is a drug-linker conjugate for ADC with potent antitumor activity by using DNA31 (a potent RNA polymerase inhibitor), linked via the ADC linker MC-VC-PABC. | Inquiry | |
| BADC-00854 | Mc-VC-PAB-SN38 | 1801838-28-7 |
| Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry |
