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Methotrexate monohydrate

  CAS No.: 6745-93-3   Cat No.: BADC-01391   Purity: 98% 4.5  

Methotrexate monohydrate is a DHhF reductase inhibitor that inhibits the enzyme dihydrofolate reductase and DNA synthesis. Therefore it is used to treat various cancers.

Methotrexate monohydrate

Structure of 6745-93-3

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Category
ADC Cytotoxin
Molecular Formula
C20H24N8O6
Molecular Weight
472.45
Shipping
Store at -20°C

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
Amethopterin monohydrate; CL14377 monohydrate; WR19039 monohydrate
IUPAC Name
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;hydrate
Canonical SMILES
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O.O
InChI
InChI=1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);1H2/t13-;/m0./s1
InChIKey
FPJYMUQSRFJSEW-ZOWNYOTGSA-N
Solubility
Soluble in DMSO
Storage
Store at -20°C

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: DBCO-Peg4-VC-PAB-MMAE | Methotrexate monohydrate
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