Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00041 | Daunorubicin hydrochloride | 23541-50-6 |
| Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. | Inquiry | |
| BADC-00038 | Doxorubicin hydrochloride | 25316-40-9 |
| Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | Inquiry | |
| BADC-00796 | Sibiromycin | 12684-33-2 |
| It is an aminoglycoside antibiotic produced by the strain of Streptosporangium sibiricum. It has anti-bacterial effect and has an inhibitory effect on reticuloendothelial sarcoma RAB-1 and oncogenic AK/LY cells. Two times of the maximum tolerated dose of intravenous administration can inhibit OZH-5 tumor and lymphosarcoma Lic-1. It has very high DNA binding affinity and cytotoxicity against cancer cell lines. | Inquiry | |
| BADC-01383 | Inebilizumab | 1299440-37-1 |
| Inebilizumab is an anti-CD19 monoclonal antibody used to treat adults with neuromyelitis optica spectrum disorders (NMOSD). | Inquiry | |
| BADC-01345 | MC-Val-Ala-SG3199 | |
| MC-Val-Ala-SG3199 is a potent cytotoxic compound. It is a potent, selective, irreversible inhibitor with a high reputation in the biomedical field. Its most important significance is in the fight against cancer, especially those that are refractory to traditional treatments. This compound triggers cell death by specifically targeting an enzyme that plays a key role in the ominous expansion and proliferation of tumors. | Inquiry | |
| BADC-01347 | Trastuzumab-MC-MMAE | |
| Trastuzumab-mc-MMAE is an ADC product consisting of an anti-HER2 antibody (Trastuzumab) conjugated to MMAE via an Mc linker. It has been used to treat breast, ovarian and lung cancer by depolymerizing microtubule MOA (mechanism of action). | Inquiry | |
| BADC-01362 | BAY 1135626 | 1404071-37-9 |
| BAY 1135626 is used to synthesize BAY 1129980. BAY 1129980 (C4.4A-ADC) is a promising therapeutic candidate for the treatment of NSCLC and other cancers expressing C4.4A. | Inquiry | |
| BADC-01365 | S-Me-DM4 | 890654-03-2 |
| S-Me-DM4 is an ADC cytotoxin molecule. It inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. | Inquiry | |
| BADC-01371 | 2',3'-cGAMP-C2-SH | 2133823-39-7 |
| 2',3'-cGAMP-C2-SH is an ADC Cytotoxin extracted from patent US20210015941. | Inquiry | |
| BADC-00361 | Combretastatin A4 | 117048-59-6 |
| Combretastatin A4 is a stilbenoid isolated from Combretum caffrum. Combretastatin A4 was shown to inhibit tubulin polymerization (IC50 = 2.2 μM). It has demonstrable antineoplastic activity. | Inquiry | |
| BADC-00029 | MC-Val-Cit-PAB-MMAE | 646502-53-6 |
| MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. | Inquiry | |
| BADC-00182 | Duocarmycin analog | |
| Duocarmycin analog has cytotoxicity for solid tumor cells that can be used for antibody-drug conjugates (ADCs). Duocarmycins and the analogs acts via binding to the minor groove of DNA and alkylating the nucleobase adenine at the N3 position, which leads to DNA damage and cancer cell death. | Inquiry | |
| BADC-00034 | Taltobulin | 228266-40-8 |
| Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. HTI-286 was a potent inhibitor of proliferation (mean IC50 = 2.5 ± 2.1 nm in 18 human tumor cell lines) and had substantially less interaction with multidrug resistance protein (P-glycoprotein) than currently used antimicrotubule agents, including paclitaxel, docetaxel, vinorelbine, or vinblastine. | Inquiry | |
| BADC-00325 | Paclitaxel | 33069-62-4 |
| Paclitaxel is a compound with anti-tumor activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. | Inquiry | |
| BADC-00791 | Illudin S | 1149-99-1 |
| Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. | Inquiry | |
| BADC-00040 | Dolastatin 10 | 110417-88-4 |
| Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibiting microtubule assembly. | Inquiry | |
| BADC-00179 | Colcemide | 477-30-5 |
| An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L. | Inquiry | |
| BADC-01393 | Irinotecan EP Impurity E (SN-38) | 86639-52-3 |
| An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. It inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. | Inquiry | |
| BADC-00037 | Methotrexate | 59-05-2 |
| Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. | Inquiry | |
| BADC-00714 | Maytansinol | 57103-68-1 |
| Maytansinol is an ansamacrolide isolated from P. verrucose. It was shown to inhibit microtubule assembly and induces microtubule disassembly in vitro. It exhibits antitumor activity. | Inquiry |
