Taltobulin trifluoroacetate - CAS 228266-41-9

Taltobulin trifluoroacetate - CAS 228266-41-9 Catalog number: BADC-00035

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Taltobulin trifluoroacetate is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.

Category
ADCs Cytotoxin
Product Name
Taltobulin trifluoroacetate
CAS
228266-41-9
Catalog Number
BADC-00035
Molecular Formula
C29H44F3N3O6
Molecular Weight
587.67
Purity
>98%
Taltobulin trifluoroacetate

Ordering Information

Catalog Number Size Price Quantity
BADC-00035 -- $-- Inquiry
Description
Taltobulin trifluoroacetate is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.
Synonyms
HTI-286; SPA-110; HTI 286; HTI-286; SPA 110; SPA110
IUPAC Name
(E,4S)-4-[[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-phenylbutanoyl]amino]butanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid; 2,2,2-trifluoroacetic acid
Canonical SMILES
CC(C)C(C=C(C)C(=O)O)N(C)C(=O)C(C(C)(C)C)NC(=O)C(C(C)(C)C1=CC=CC=C1)NC.C(=O)(C(F)(F)F)O
InChI
InChI=1S/C27H43N3O4.C2HF3O2/c1-17(2)20(16-18(3)25(33)34)30(10)24(32)22(26(4,5)6)29-23(31)21(28-9)27(7,8)19-14-12-11-13-15-19;3-2(4,5)1(6)7/h11-17,20-22,28H,1-10H3,(H,29,31)(H,33,34);(H,6,7)/b18-16+;/t20-,21-,22-;/m1./s1
InChIKey
SHWPCKJNFBDPFA-LPWSJWOVSA-N
Appearance
Solid Power
Shelf Life
≥12 months if stored properly
Shipping
Room temperature, or blue ice upon request.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Taltobulin trifluoroacetate
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