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Taltobulin trifluoroacetate

  CAS No.: 228266-41-9   Cat No.: BADC-00035   Purity: >98% 4.5  

Taltobulin trifluoroacetate is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.

Taltobulin trifluoroacetate

Structure of 228266-41-9

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Category
ADC Cytotoxin
Molecular Formula
C29H44F3N3O6
Molecular Weight
587.67
Shipping
Room temperature, or blue ice upon request.

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
HTI-286; SPA-110; HTI 286; HTI-286; SPA 110; SPA110
IUPAC Name
(E,4S)-4-[[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-phenylbutanoyl]amino]butanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid; 2,2,2-trifluoroacetic acid
Canonical SMILES
CC(C)C(C=C(C)C(=O)O)N(C)C(=O)C(C(C)(C)C)NC(=O)C(C(C)(C)C1=CC=CC=C1)NC.C(=O)(C(F)(F)F)O
InChI
InChI=1S/C27H43N3O4.C2HF3O2/c1-17(2)20(16-18(3)25(33)34)30(10)24(32)22(26(4,5)6)29-23(31)21(28-9)27(7,8)19-14-12-11-13-15-19;3-2(4,5)1(6)7/h11-17,20-22,28H,1-10H3,(H,29,31)(H,33,34);(H,6,7)/b18-16+;/t20-,21-,22-;/m1./s1
InChIKey
SHWPCKJNFBDPFA-LPWSJWOVSA-N
Appearance
Solid Power
Shelf Life
≥12 months if stored properly
Shipping
Room temperature, or blue ice upon request.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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