Mal-VC-PAB-DM1 - CAS 1464051-44-2

Mal-VC-PAB-DM1 - CAS 1464051-44-2 Catalog number: BADC-00601

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Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB.

General Information

Category
ADCs Cytotoxin with Linkers
Product Name
Mal-VC-PAB-DM1
CAS
1464051-44-2
Catalog Number
BADC-00601
Molecular Formula
C61H82ClN9O17
Molecular Weight
1248.81
Target
Microtubule/Tubulin

Chemical Structure

  • Mal-VC-PAB-DM1
Shipping
Room temperature
Canonical SMILES
C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

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Historical Records: Mal-PEG6-NHS ester | Mal-PEG4-NHS | Salsoline | Maytansine | OSu-PEG4-vc-PAB-DMEA-Duocarmycin DM | DBCO-PEG4-DMEA-PNU159682 | Calicheamicin | MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA | Mal-VC-PAB-DM1
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