Dimethyl-SGD-1882

Dimethyl-SGD-1882 Catalog number: BADC-01486

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Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly efficient DNA alkylator (DNA alkylator), which can be used as the toxin moiety of antibody drug conjugate (ADC). PBD Dimer is a DNA alkylating agent that inhibits DNA replication.

Category
ADCs Cytotoxin
Product Name
Dimethyl-SGD-1882
Catalog Number
BADC-01486
Molecular Formula
C44H43N5O7
Molecular Weight
753.84
Dimethyl-SGD-1882

Ordering Information

Catalog Number Size Price Quantity
BADC-01486 -- $-- Inquiry
Description
Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly efficient DNA alkylator (DNA alkylator), which can be used as the toxin moiety of antibody drug conjugate (ADC). PBD Dimer is a DNA alkylating agent that inhibits DNA replication.
Synonyms
Dimethyl-PBD dimer
IUPAC Name
(6aR)-3-[3-[[(6aR)-2-methoxy-8-(4-methoxyphenyl)-6a-methyl-11-oxo-7H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]propoxy]-8-(4-aminophenyl)-2-methoxy-6a-methyl-7H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one
Canonical SMILES
CC12CC(=CN1C(=O)C3=CC(=C(C=C3N=C2)OCCCOC4=C(C=C5C(=C4)N=CC6(CC(=CN6C5=O)C7=CC=C(C=C7)OC)C)OC)OC)C8=CC=C(C=C8)N
InChI
InChI=1S/C44H43N5O7/c1-43-21-29(27-7-11-31(45)12-8-27)23-48(43)41(50)33-17-37(53-4)39(19-35(33)46-25-43)55-15-6-16-56-40-20-36-34(18-38(40)54-5)42(51)49-24-30(22-44(49,2)26-47-36)28-9-13-32(52-3)14-10-28/h7-14,17-20,23-26H,6,15-16,21-22,45H2,1-5H3/t43-,44-/m1/s1
InChIKey
MKHWXCZGNPQRBL-NDOUMJCMSA-N
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: FR-901464 | Dimethyl-SGD-1882
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