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MB-VC-MGBA

  CAS No.: 932744-62-2   Cat No.: BADC-01465 4.5  

MB-VC-MGBA is a part of antibody drug conjugates, which is formed by linking DNA alkylating agent MGBA and ADC linker MB-VC.

MB-VC-MGBA

Structure of 932744-62-2

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Category
ADC Cytotoxin
Molecular Formula
C56H65ClN12O10
Molecular Weight
1101.64

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
MB-VC-MGBA
IUPAC Name
[(1S)-3-[5-[[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[2-[4-(2,5-dioxopyrrol-1-yl)butanoylamino]ethylamino]-3-methylbutanoyl]amino]pentanoyl]amino]benzoyl]amino]-1H-indole-2-carbonyl]-1-(chloromethyl)-1,2-dihydrobenzo[e]indol-5-yl] 4-methylpiperazine-1-carboxylate
Canonical SMILES
CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC3=C(C=C2)NC(=C3)C(=O)N4CC(C5=C4C=C(C6=CC=CC=C65)OC(=O)N7CCN(CC7)C)CCl)NCCNC(=O)CCCN8C(=O)C=CC8=O
InChI
InChI=1S/C56H65ClN12O10/c1-33(2)50(60-22-21-59-46(70)11-7-23-68-47(71)18-19-48(68)72)53(75)65-42(10-6-20-61-55(58)77)52(74)62-37-14-12-34(13-15-37)51(73)63-38-16-17-41-35(28-38)29-43(64-41)54(76)69-32-36(31-57)49-40-9-5-4-8-39(40)45(30-44(49)69)79-56(78)67-26-24-66(3)25-27-67/h4-5,8-9,12-19,28-30,33,36,42,50,60,64H,6-7,10-11,20-27,31-32H2,1-3H3,(H,59,70)(H,62,74)(H,63,73)(H,65,75)(H3,58,61,77)/t36-,42+,50+/m1/s1
InChIKey
LWUVZRWVARAEMO-MUYWJSLASA-N

MB-VC-MGBA, a specialized compound utilized in scientific research and biotechnological applications, offers a spectrum of versatile functions. Here are four key applications of MB-VC-MGBA:

Protein Modification Studies: In the realm of biochemical studies, MB-VC-MGBA emerges as a pivotal reagent for effecting protein modifications. By forming covalent bonds with specific amino acid residues, it enables researchers to delve into the intricate terrain of protein structure and function. This modification process serves as a catalyst for unraveling the enigmatic world of protein interactions and their multifaceted roles in diverse biological processes.

Biosensor Development: Embarking on the journey of biosensor innovation, MB-VC-MGBA assumes a central role owing to its unique properties as a reactive marker. Upon integration into biosensor frameworks, it elevates the detection prowess for biological molecules with pinpoint specificity. This application bears immense significance in the realms of environmental surveillance, medical diagnostics, and the vigilant scrutiny of food safety standards.

Enzyme Activity Analysis: Within the intricate domain of enzyme assays, MB-VC-MGBA takes center stage in the meticulous examination of enzyme activities and kinetics. Serving as both a substrate and an inhibitor, it unravels the inner workings of enzyme mechanisms and catalytic efficiencies. Such revelations play a pivotal role in the realms of drug discovery and the strategic design of enzyme-driven industrial processes.

Fluorescence Labeling: As a luminescent labeling agent in the sprawling landscape of molecular biology experiments, MB-VC-MGBA shines brightly. When coalesced with biomolecules, it spearheads the visualization and monitoring of cellular processes through the lens of fluorescence microscopy. This transformative application stands as a cornerstone in live cell imaging endeavors and the exploration of dynamic biological phenomena.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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