MPB-VC-PAB-DM1
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MPB-VC-PAB-DM1 Catalog number: BADC-01411

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MPB-VC-PAB-DM1 is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Cytotoxin with Linkers
Product Name
MPB-VC-PAB-DM1
Catalog Number
BADC-01411
Molecular Formula
C65H82ClN9O17
Molecular Weight
1296.87
MPB-VC-PAB-DM1

Ordering Information

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BADC-01411 -- $--
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Description
MPB-VC-PAB-DM1 is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).
IUPAC Name
(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(((4-((S)-2-((S)-2-(4-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)butanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl)oxy)carbonyl)-N-methyl-L-alaninate
InChI
InChI=1S/C65H82ClN9O17/c1-36(2)56(71-51(76)18-12-15-40-21-25-44(26-22-40)75-52(77)27-28-53(75)78)59(81)70-45(16-13-29-68-61(67)83)58(80)69-43-23-19-41(20-24-43)35-89-63(85)73(7)39(5)60(82)91-50-33-54(79)74(8)46-31-42(32-47(87-9)55(46)66)30-37(3)14-11-17-49(88-10)65(86)34-48(90-62(84)72-65)38(4)57-64(50,6)92-57/h11,14,17,19-28,31-32,36,38-39,45,48-50,56-57,86H,12-13,15-16,18,29-30,33-35H2,1-10H3,(H,69,80)(H,70,81)(H,71,76)(H,72,84)(H3,67,68,83)/b17-11+,37-14+/t38-,39+,45+,48+,49-,50+,56+,57+,64+,65+/m1/s1
InChIKey
OXFFVXZIYNKAAK-GDHWPVNGSA-N
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: MPB-VC-PAB-DM1
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
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BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
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BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
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