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CAS No.: 1311459-55-8
Cat No.: BADC-00581
4.5 
3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate is an activated acrylate ADC linker enabling Michael addition conjugation with antibodies, promoting stable and efficient payload attachment for improved antibody-drug conjugate efficacy.
Structure of 1311459-55-8
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3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate, a functional monomer, has various applications in polymer and material science fields. Here are some key applications of 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate:
Bioconjugation: This acrylate derivative is used in bioconjugation techniques to link biomolecules, such as proteins and peptides, with synthetic polymers. By creating covalent bonds, researchers can develop hybrid materials with unique properties for drug delivery, diagnostics, and tissue engineering. This facilitates the creation of advanced biomaterials that leverage the best properties of both biological and synthetic components.
Surface Modification: 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate can be used to modify surfaces of various substrates, enhancing their wettability, adhesion, and biocompatibility. Through surface grafting or coating, this compound introduces functional groups that can interact with specific target molecules or cells. This has applications in developing advanced medical devices, biosensors, and biocompatible coatings.
Controlled Polymerization: This monomer is employed in controlled polymerization techniques such as atom transfer radical polymerization (ATRP) to synthesize well-defined and functionalized polymers. By precisely controlling the molecular architecture, researchers can tailor the properties of resulting polymers for applications in drug delivery systems, smart materials, and responsive hydrogels. This enables the design of materials with specific functions and behaviors under different environmental conditions.
Crosslinking Agent: In the context of polymer chemistry, 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate serves as an efficient crosslinking agent. By incorporating this monomer into polymer matrices, it can provide additional mechanical strength, thermal stability, and chemical resistance. This is particularly useful in producing high-performance materials for coatings, adhesives, and composite applications.
3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate
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3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate
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