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2,5-dioxopyrrolidin-1-yl 1-(cyclooct-2-ynyloxy)-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate

  CAS No.:   Cat No.: BADC-00421   Purity: 98% 4.5  

2,5-dioxopyrrolidin-1-yl 1-(cyclooct-2-ynyloxy)-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate is a highly intricate and multifaceted substance that emerges as an exceedingly powerful agent employed within the biomedical realm. Manifesting its efficacy in combating a myriad of ailments including cancer, inflammation, and bacterial infections, this compound boasts the capacity to extensively navigate and perturb distinct biochemical routes intrinsic to cellular mechanisms.

2,5-dioxopyrrolidin-1-yl 1-(cyclooct-2-ynyloxy)-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate

Structure of

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Category
ADC Linker
Molecular Formula
C25H38N2O10
Molecular Weight
526.58
Shipping
-20°C (International: -20°C)
Shipping
-20°C

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
Cyclooctyne-PEG4-Osu;Cyclooctyne-PEG4-NHS ester
Appearance
Soild powder
Shipping
-20°C (International: -20°C)
Storage
-20°C

2,5-Dioxopyrrolidin-1-yl 1-(cyclooct-2-ynyloxy)-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate, a highly intricate chemical compound, finds diverse applications in the realms of chemical biology and material science. Here are four key applications presented with high perplexity and burstiness:

Bioconjugation: Widely utilized in bioconjugation methodologies, this compound serves as a versatile linker for connecting biomolecules such as proteins, peptides, or nucleic acids to various substrates. Its reactivity enables the formation of stable covalent bonds, facilitating the attachment of biologically active molecules to polymers, nanoparticles, or surfaces. This pivotal role is essential for the development of targeted drug delivery systems and diagnostic tools, enhancing precision in biomedical applications.

Drug Delivery Systems: Employed as a fundamental element in creating intricate drug delivery systems, this compound acts as a crucial linker for binding therapeutic agents. By enabling the controlled release of drugs at specific sites within the body, it enhances the efficacy of treatment while minimizing potential side effects. This targeted delivery mechanism revolutionizes the field of pharmacology, paving the way for personalized and efficient medication administration.

Material Science: Within the domain of material science, this compound serves as a catalyst for surface modification and the creation of functionalized materials with tailored properties. Its usage extends to attaching bioactive molecules such as enzymes or antibodies to diverse substrates, augmenting their functional capabilities. This application drives innovation in developing cutting-edge biosensors, biochips, and other advanced diagnostic devices, revolutionizing the interface between biology and material engineering.

Chemical Biology Studies: At the intersection of chemical biology, this compound plays a pivotal role in probing protein interactions and enzyme mechanisms. By facilitating the linkage of small molecules or probes to proteins, researchers can delve into binding sites, reaction dynamics, and cellular processes with enhanced clarity. This investigative approach accelerates the discovery of novel drug targets and deepens our comprehension of intricate biochemical pathways, shaping the landscape of modern biological research.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Fmoc-N-amido-PEG2-propionic acid | Phe-Lys(Trt)-PAB | 3-azidopropanoate-N-hydroxysuccinimide ester | Propargyl-O-C1-amido-PEG3-C2-NHS ester | Azido-PEG1-Val-Cit-PABC-PNP | (E)-Cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate | N-succinimidyl-6-(2-pyridyldithio)capronate | N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide | AcLys-PABC-VC-Aur0101 intermediate-1 | Aminooxy-PEG2-bis-PEG3-BCN | 2,5-dioxopyrrolidin-1-yl 1-(cyclooct-2-ynyloxy)-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
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