webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide

  CAS No.: 1226394-74-6   Cat No.: BADC-00564 4.5  

N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide serves as a reactive ADC linker with aldehyde groups, facilitating selective antibody conjugation and enhanced targeted payload delivery.

N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide

Structure of 1226394-74-6

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C18H19NO3
Molecular Weight
297.35
Shipping
Room temperature

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
IUPAC Name
N-[2-(2,4-dimethylphenoxy)ethyl]-4-formylbenzamide
Canonical SMILES
CC1=CC(=C(C=C1)OCCNC(=O)C2=CC=C(C=C2)C=O)C
InChI
InChI=1S/C18H19NO3/c1-13-3-8-17(14(2)11-13)22-10-9-19-18(21)16-6-4-15(12-20)5-7-16/h3-8,11-12H,9-10H2,1-2H3,(H,19,21)
InChIKey
WGBXLVWZHIWRLN-UHFFFAOYSA-N
Shipping
Room temperature

N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide is a versatile compound with significant applications in the development of targeted therapies, especially in cancer treatment. Its structure, featuring a formylbenzamide group, allows it to interact selectively with biological targets involved in tumor growth and metastasis. By serving as a key component in targeted drug delivery systems, it facilitates the precise delivery of therapeutic agents to cancer cells, improving efficacy while minimizing off-target effects and damage to healthy tissues. This makes it a promising candidate for improving the precision of cancer therapies.

Another critical application of N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide is in the design of small-molecule inhibitors targeting specific enzymes or proteins involved in cancer cell proliferation. The dimethylphenoxyethyl group enhances the compound's lipophilicity, improving its ability to cross cell membranes and bind to intracellular targets. These properties enable the compound to inhibit key signaling pathways that drive cancer progression, such as those mediated by kinases or proteases, potentially leading to reduced tumor growth and increased therapeutic effectiveness in cancer treatment.

In addition to cancer therapy, N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide is being explored for its potential in diagnostic imaging applications. By conjugating the compound with imaging agents, such as fluorescent dyes or radionuclides, it can be used to target specific cancer cells for precise detection. This application allows for non-invasive imaging of tumor sites, enabling the monitoring of disease progression, assessing the effectiveness of treatments, and assisting in surgical decision-making. Such imaging capabilities are critical for the advancement of personalized medicine in oncology.

The compound also has potential in the development of anti-inflammatory agents. The formylbenzamide group can interact with key inflammatory pathways, such as those mediated by cyclooxygenases or cytokines. By modulating these pathways, N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide could serve as a lead compound for the development of novel drugs aimed at treating chronic inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. Targeting specific molecular mechanisms involved in inflammation can provide more effective therapies with fewer side effects compared to conventional treatments.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Boc-Gly-Gly-Phe-Gly-OH | MA-PEG4-VA-PBD | (2S,4R)-1-((S)-17-Amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | Fmoc-N-amido-PEG2-propionic acid | Phe-Lys(Trt)-PAB | 3-azidopropanoate-N-hydroxysuccinimide ester | Propargyl-O-C1-amido-PEG3-C2-NHS ester | Azido-PEG1-Val-Cit-PABC-PNP | (E)-Cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate | N-succinimidyl-6-(2-pyridyldithio)capronate | N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide
Send Inquiry
Verification code
Inquiry Basket