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N-(2-(2, 4-Dimethylphenoxy)ethyl)-4-formylbenzamide is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00564 | -- | $-- | Inquiry |
N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide is a versatile compound with significant applications in the development of targeted therapies, especially in cancer treatment. Its structure, featuring a formylbenzamide group, allows it to interact selectively with biological targets involved in tumor growth and metastasis. By serving as a key component in targeted drug delivery systems, it facilitates the precise delivery of therapeutic agents to cancer cells, improving efficacy while minimizing off-target effects and damage to healthy tissues. This makes it a promising candidate for improving the precision of cancer therapies.
Another critical application of N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide is in the design of small-molecule inhibitors targeting specific enzymes or proteins involved in cancer cell proliferation. The dimethylphenoxyethyl group enhances the compound's lipophilicity, improving its ability to cross cell membranes and bind to intracellular targets. These properties enable the compound to inhibit key signaling pathways that drive cancer progression, such as those mediated by kinases or proteases, potentially leading to reduced tumor growth and increased therapeutic effectiveness in cancer treatment.
In addition to cancer therapy, N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide is being explored for its potential in diagnostic imaging applications. By conjugating the compound with imaging agents, such as fluorescent dyes or radionuclides, it can be used to target specific cancer cells for precise detection. This application allows for non-invasive imaging of tumor sites, enabling the monitoring of disease progression, assessing the effectiveness of treatments, and assisting in surgical decision-making. Such imaging capabilities are critical for the advancement of personalized medicine in oncology.
The compound also has potential in the development of anti-inflammatory agents. The formylbenzamide group can interact with key inflammatory pathways, such as those mediated by cyclooxygenases or cytokines. By modulating these pathways, N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide could serve as a lead compound for the development of novel drugs aimed at treating chronic inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. Targeting specific molecular mechanisms involved in inflammation can provide more effective therapies with fewer side effects compared to conventional treatments.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
