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Cleavable Linker
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Cleavable Linker

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Catalog Product Name CAS Number
BADC-00486 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate 107348-47-0
2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate is a pyridyl disulfide-based ADC linker with NHS ester functionality, facilitating stable antibody-payload conjugation and controlled intracellular payload release to enhance ADC specificity and efficacy. Inquiry
BADC-00487 perfluorophenyl 3-(pyridin-2-yldisulfanyl)propanoate 160580-70-1
Perfluorophenyl 3-(pyridin-2-yldisulfanyl)propanoate is a perfluorophenyl ester-based ADC linker enabling efficient conjugation and cleavable disulfide bonds for controlled payload release, improving ADC targeting and anti-tumor efficacy. Inquiry
BADC-00488 2,5-dioxo-1-(3-(pyridin-2-yldisulfanyl)propanoyloxy)pyrrolidine-3-sulfonic acid 121115-30-8
SPDP-sulfo is a biomedical compound that has demonstrated its ability to combat various diseases. Because of its ability to expertly inhibit the tailor-made enzymes that control the progression of diseases such as cancer and inflammation, it emerges as a potential disease intervention tool. Inquiry
BADC-00489 4-((S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanamido)benzyl 2-(pyridin-2-yldisulfanyl)ethylcarbamate 1610769-13-5
PDP-C1-Ph-Val-Cit is a small molecule compound. It blocks specific enzymes involved in harmful processes of tumor expansion and metastasis, effectively inhibiting cancer progression. Inquiry
BADC-00490 Boc-Phe-(Alloc)Lys-PAB-PNP 1160844-44-9
Boc-Phe-(Alloc)Lys-PAB-PNP is a complex biomedical compound being investigated as an innovative treatment for a variety of diseases, especially cancer. Known for its powerful properties, it effectively halts tumor progression through targeted neutralization of unique enzymes and pathways. Inquiry
BADC-00491 Cbz-Phe-(Alloc)Lys-PAB-PNP 159857-90-6
Cbz-Phe-(Alloc)Lys-PAB-PNP is an important biomedical chemical product that has emerged as a potential therapeutic agent against various diseases. It has demonstrated outstanding capabilities as a candidate compound for targeted therapy against various malignancies, including breast and prostate cancer. This revolutionary compound, Cbz-Phe-(Alloc)Lys-PAB-PNP, utilizes its unique molecular structure to produce profound inhibitory effects on the proliferation of malignant cells. Inquiry
BADC-00492 Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP 253863-34-2
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugate (ADC) synthesis. Featuring a PAB-PNP self-immolative spacer, it ensures payload release upon cleavage. Ideal for targeted drug delivery, this linker supports precise bioconjugation strategies in cancer therapeutics. Inquiry
BADC-00493 Fmoc-Ala-Ala-Asn-PAB-PNP 1834516-06-1
Fmoc-Ala-Ala-Asn-PAB-PNP is an excellent and highly discriminating inhibitor widely used in biomedicine for multiple purposes. It is widely used in the field of drug development, especially in the targeted detection and attenuation of malignancies and cancers. Inquiry
BADC-00494 Ala-Ala-Asn-PAB 2149584-00-7
Ala-Ala-Asn-PAB is a peptide derivative widely used in biomedical fields. The product is known for its superior chemical properties, which are highly advantageous in targeted drug delivery and enhanced therapeutic efficacy. Its broad applications include drug research for a variety of diseases, especially cancer. Inquiry
BADC-00495 Fmoc-Phe-Lys(Trt)-PAB-PNP 1116086-09-9
Fmoc-Phe-Lys(Trt)-PAB-PNP is a protected peptide-based ADC linker, enabling site-specific conjugation of payloads to antibodies. Its PAB-PNP structure allows for stable yet cleavable drug attachment, suitable for antibody-drug conjugate development and controlled drug release in oncology. Inquiry
BADC-00497 sulfo-LC-SPDP 150244-18-1
sulfo-LC-SPDP is a water-soluble, cleavable ADC crosslinker featuring a disulfide bond. Widely used in bioconjugation and ADC linker design, it enables reversible linkage of thiol-containing biomolecules under reducing conditions, ideal for antibody-drug conjugate construction. Inquiry
BADC-00582 Fmoc-PEG4-NHS ester 1314378-14-7
Fmoc-PEG4-NHS ester is a PEG derivative containing an Fmoc-protected amine and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic conditions to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Inquiry
BADC-00586 Boc-NMe-Val-Val-Dil-Dap-OH 1352202-13-1
Boc-NMe-Val-Val-Dil-Dap-OH is a protected peptide ADC linker intermediate with a dipeptide sequence designed for enzyme-sensitive cleavage and controlled payload release in antibody-drug conjugates. Keywords: ADC linker, peptide linker, Boc protection, enzyme-sensitive, controlled release. Inquiry
BADC-00590 DBCO-C6-NHS ester 1384870-47-6
DBCO-C6-NHS ester is a click-ready ADC linker combining a DBCO group for copper-free conjugation with an NHS ester for amine coupling. Suitable for site-selective antibody labeling in the development of stable antibody-drug conjugates. Inquiry
BADC-00591 DBCO-NHS ester 3 1393350-27-0
DBCO-NHS ester 3 is a bioorthogonal ADC linker with DBCO for rapid click conjugation and NHS ester for amine coupling. Supports efficient antibody conjugation and targeted payload delivery in ADC development. Inquiry
BADC-00595 6-(Boc-amino)hexyl bromide 142356-33-0
6-(Boc-amino)hexyl bromide is a Boc-protected alkyl linker used in ADC synthesis to introduce hydrophobic spacers. Its bromide group facilitates nucleophilic substitution, allowing for tailored payload conjugation and modulation of linker stability and drug release kinetics. Inquiry
BADC-00621 CL2A 1846605-04-6
CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker. Inquiry
BADC-00626 4-Formyl-N-(2-Methoxyethyl)benzamide 199679-16-8
4-Formyl-N-(2-Methoxyethyl)benzamide is an aldehyde-functionalized ADC linker intermediate enabling selective conjugation via Schiff base formation, enhancing payload attachment stability in antibody-drug conjugates. Keywords: ADC linker, aldehyde linker, selective conjugation, Schiff base, payload attachment. Inquiry
BADC-00641 SPDMB 2101206-29-3
SPDMB is a specialized disulfide-based ADC linker facilitating controlled, redox-sensitive drug release and stable antibody-payload conjugation in targeted therapeutics. Inquiry
BADC-00657 SPDMV-sulfo 2101206-86-2
SPDMV-sulfo is a water-soluble, cleavable pyridyl disulfide ADC linker with sulfonate groups, enhancing conjugation efficiency and payload release in aqueous antibody-drug conjugate synthesis. Inquiry
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