Name: Cbz-Phe-(Alloc)Lys-PAB-PNP
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Synonyms

[4-[[(2S)-1-amino-1-oxo-6-(prop-2-enoxycarbonylamino)hexan-2-yl]-[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate;

IUPAC Name

[4-[[(2S)-1-amino-1-oxo-6-(prop-2-enoxycarbonylamino)hexan-2-yl]-[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate

SMILES

C=CCOC(=O)NCCCCC(C(=O)N)N(C1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4

InChI

InChI=1S/C41H43N5O11/c1-2-25-54-39(49)43-24-10-9-15-36(37(42)47)45(32-18-16-31(17-19-32)28-56-41(51)57-34-22-20-33(21-23-34)46(52)53)38(48)35(26-29-11-5-3-6-12-29)44-40(50)55-27-30-13-7-4-8-14-30/h2-8,11-14,16-23,35-36H,1,9-10,15,24-28H2,(H2,42,47)(H,43,49)(H,44,50)/t35-,36-/m0/s1

InChIKey

ZDMMWLUQPVUZQI-ZPGRZCPFSA-N

Appearance

Soild powder

Shipping

Room temperature, or blue ice upon request.

Cbz-Phe-(Alloc)Lys-PAB-PNP, a synthetic compound essential in peptide synthesis and biochemical research, finds diverse applications.

Peptide Synthesis: Serving as a foundational element in crafting intricate peptides, Cbz-Phe-(Alloc)Lys-PAB-PNP plays a pivotal role in peptide assembly. Its distinct protective groups enable selective deprotection and coupling reactions, ensuring the precise construction of peptide chains. This precision is critical for generating ultra-pure peptides for both research endeavors and therapeutic interventions.

Drug Development: Within the realm of pharmaceutical innovation, Cbz-Phe-(Alloc)Lys-PAB-PNP emerges as a potent tool for engineering peptide-based drugs. By integrating this compound into peptide synthesis protocols, scientists can fabricate and evaluate novel therapeutic peptides characterized by exceptional specificity and potency. This application holds particular significance in the quest for treatments targeting diseases where peptide-based therapies exhibit significant potential.

Bioconjugation: Instrumental in the realm of bioconjugation methodologies, Cbz-Phe-(Alloc)Lys-PAB-PNP facilitates the linking of peptides to various molecules for multifaceted applications. This compound enables the modification of peptides with diverse functional groups, such as fluorophores and enzymes.

Proteomics Research: In the domain of proteomics, Cbz-Phe-(Alloc)Lys-PAB-PNP is harnessed to delve into protein interactions and functionalities. By synthesizing tagged peptides utilizing this compound, researchers can explore protein binding sites and unravel intricate protein-protein interactions. This exploration aids in deciphering cellular processes and identifying potential targets for drug development, paving the way for groundbreaking discoveries in the realm of proteomics.