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4-Formyl-N-(2-Methoxyethyl)benzamide

  CAS No.: 199679-16-8   Cat No.: BADC-00626 4.5  

4-Formyl-N-(2-Methoxyethyl)benzamide is an aldehyde-functionalized ADC linker intermediate enabling selective conjugation via Schiff base formation, enhancing payload attachment stability in antibody-drug conjugates. Keywords: ADC linker, aldehyde linker, selective conjugation, Schiff base, payload attachment.

4-Formyl-N-(2-Methoxyethyl)benzamide

Structure of 199679-16-8

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ADC Linker
Molecular Formula
C11H13NO3
Molecular Weight
207.23
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Synonyms
4-formyl-n-(2-methoxyethyl)benzamide
IUPAC Name
4-formyl-N-(2-methoxyethyl)benzamide
Canonical SMILES
COCCNC(=O)C1=CC=C(C=C1)C=O
InChI
InChI=1S/C11H13NO3/c1-15-7-6-12-11(14)10-4-2-9(8-13)3-5-10/h2-5,8H,6-7H2,1H3,(H,12,14
InChIKey
IJFVPKBUTPRZAM-UHFFFAOYSA-N
Shipping
Room temperature, or blue ice upon request.

4-Formyl-N-(2-Methoxyethyl)benzamide, known for its unique chemical properties, finds significant application in organic synthesis. Often utilized as an intermediate, this compound plays a crucial role in the formation of complex organic molecules. Its structure facilitates various reactions, making it an essential building block in the pharmaceutical industry for the synthesis of bioactive molecules. The high reactivity, coupled with its stability, allows chemists to employ this compound in multiple steps of synthetic pathways, ensuring the efficient and streamlined production of target compounds.

In the field of material science, 4-Formyl-N-(2-Methoxyethyl)benzamide is instrumental in developing advanced materials with specific properties. Researchers exploit its aldehyde group to introduce functional groups into polymer chains, enhancing the material’s characteristics such as thermal stability, mechanical strength, and conductivity. This application is particularly relevant in the production of high-performance polymers and composites used in electronics, aerospace, and automotive industries, where the material’s performance can be critically enhanced by chemical modifications introduced using 4-Formyl-N-(2-Methoxyethyl)benzamide.

Another significant application of 4-Formyl-N-(2-Methoxyethyl)benzamide is in the formulation of specialized coatings and adhesives. The compound’s reactivity with various amines and other nucleophiles enables the creation of robust cross-linked networks. These properties are highly valued in industrial applications where durability and resistance to environmental factors are required. For instance, coatings derived from this compound offer superior protection against corrosion and wear, making them suitable for heavy-duty machinery and infrastructure. Similarly, adhesives formed using this chemical exhibit strong bonding capabilities, essential for construction and repair work.

In the realm of biochemical research, 4-Formyl-N-(2-Methoxyethyl)benzamide serves as a valuable probe for studying enzyme mechanisms and interactions. Its aldehyde functional group can be specifically targeted by enzyme active sites, allowing researchers to investigate the binding interactions and catalytic processes in detail. This application is crucial for drug discovery and development, where understanding enzyme behavior can lead to the identification of new therapeutic targets and the design of enzyme inhibitors. By utilizing this compound, biochemists can elucidate complex biochemical pathways and contribute to the development of more effective pharmaceutical agents.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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