6-(Boc-amino)hexyl bromide - CAS 142356-33-0

6-(Boc-amino)hexyl bromide - CAS 142356-33-0 Catalog number: BADC-00595

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Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC).

Category
ADCs Linker
Product Name
6-(Boc-amino)hexyl bromide
CAS
142356-33-0
Catalog Number
BADC-00595
Molecular Formula
C11H22BrNO2
Molecular Weight
280.20
6-(Boc-amino)hexyl bromide

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BADC-00595 -- $--
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Description
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC).
Synonyms
tert-butyl N-(6-bromohexyl)carbamate
IUPAC Name
tert-butyl N-(6-bromohexyl)carbamate
Canonical SMILES
CC(C)(C)OC(=O)NCCCCCCBr
InChI
InChI=1S/C11H22BrNO2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9H2,1-3H3,(H,13,14)
InChIKey
NXQXVXILNVTMNA-UHFFFAOYSA-N
Density
1.189 g/cm3
LogP
3.85730
Appearance
Colourless liquid
Purity
98 %
Shipping
Room temperature, or blue ice upon request.
Storage
2-8 ℃
Signal Word
Danger
Boiling Point
340.1 ℃ at 760 mmHg
1.Synthesis of Peptidomimics Through Sugar-Based Scaffolds
Yves Le Merrer, Lydie Poitout, Jean-Claude Depezay
Poor oral bioavailability, low metabolic stability towards proteolysis and rapid excretion via both liver and kidneys displayed by innumerable peptides of potential therapeutic value has generated an intensive search for peptidomimics. A possible approach of such nonpeptidal peptidomimics is to replace the peptide by a scaffold that distributes in the space the peptidal side chains of amino acids essential for biological activity and mimics the bioactive conformation of the peptide.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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