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Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00595 | -- | $-- |
6-(Boc-amino)hexyl bromide, a versatile molecule in organic synthesis and chemical biology, finds diverse applications across various fields. Here are four key applications presented with a high degree of perplexity and burstiness:
Peptide Synthesis: Integral to peptide synthesis, 6-(Boc-amino)hexyl bromide plays a pivotal role as a protecting group for amino functionalities. By temporarily shielding reactive amino groups, it facilitates the meticulous and controlled assembly of peptide chains in a step-wise manner. This precision is essential in yielding peptides of exceptional purity and specific sequences tailored for both research and therapeutic endeavors.
Click Chemistry: Positioned as a fundamental building block in click chemistry, this compound enables the intricate formation of complex molecules through bioorthogonal ligation. Capable of being functionalized with various azide or alkyne groups, it expedites the selective and rapid establishment of covalent bonds under mild conditions. This application proves particularly advantageous for labeling biomolecules and fostering the innovation of novel materials with unique properties.
Drug Development: In the realm of medicinal chemistry, 6-(Boc-amino)hexyl bromide finds utility in incorporating Boc-protected amino groups into pharmaceutical candidates. This modification can significantly enhance the pharmacokinetic attributes of drugs, including enhancing stability and bioavailability. Moreover, it plays a crucial role in the development of prodrugs, which are inert compounds that undergo metabolic transformation into active therapeutics within the body.
Polymer Chemistry: Employed as a key component in polymer chemistry, this compound serves as a valuable chain extender and cross-linking agent in the synthesis of functionalized polymers. By integrating Boc-amino groups into polymer structures, researchers can engineer materials with tailored physical and chemical characteristics. These specialized polymers find applications in diverse fields such as drug delivery systems, tissue engineering, and the creation of responsive hydrogels, showcasing the versatility and adaptability of this compound in polymer chemistry.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
