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4-Formyl-N-(2-Phenoxyethyl)benzamide

  CAS No.: 1225575-00-7   Cat No.: BADC-00529 4.5  

4-Formyl-N-(2-Phenoxyethyl)benzamide is an aldehyde-functionalized ADC linker facilitating bioorthogonal conjugation, promoting site-specific antibody attachment and controlled payload release in antibody-drug conjugate development.

4-Formyl-N-(2-Phenoxyethyl)benzamide

Structure of 1225575-00-7

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ADC Linker
Molecular Formula
C16H15NO3
Molecular Weight
269.3
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Room temperature, or blue ice upon request.

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IUPAC Name
4-formyl-N-(2-phenoxyethyl)benzamide
Canonical SMILES
C1=CC=C(C=C1)OCCNC(=O)C2=CC=C(C=C2)C=O
InChI
InChI=1S/C16H15NO3/c18-12-13-6-8-14(9-7-13)16(19)17-10-11-20-15-4-2-1-3-5-15/h1-9,12H,10-11H2,(H,17,19)
InChIKey
LWKKJRXIXTVRBG-UHFFFAOYSA-N
Shipping
Room temperature, or blue ice upon request.

4-Formyl-N-(2-Phenoxyethyl)benzamide is a versatile organic compound with significant applications in pharmaceutical development. It is primarily used as an intermediate in the synthesis of various biologically active molecules. One of its critical applications is in the development of anti-cancer agents. As cancer remains a leading cause of death worldwide, continuous research and development efforts are crucial. 4-Formyl-N-(2-Phenoxyethyl)benzamide serves as a vital building block in creating compounds that can inhibit cancer cell growth or induce apoptosis in malignant cells. These anti-cancer agents, derived from this benzamide derivative, show promise in clinical trials, offering new hope to patients suffering from various types of cancer.

Another significant application of 4-Formyl-N-(2-Phenoxyethyl)benzamide is in the creation of anti-inflammatory drugs. Inflammation is a common pathway in numerous diseases, including arthritis, cardiovascular diseases, and neurodegenerative disorders. By acting as a precursor to molecules that modulate the inflammatory response, this compound contributes to developing medications that can alleviate symptoms and improve the quality of life for patients with chronic inflammatory conditions. The specificity and efficiency of these derivatives in targeting inflammatory pathways have made them a focal point in pharmaceutical research.

4-Formyl-N-(2-Phenoxyethyl)benzamide also finds use in developing antimicrobial agents. The rise of antibiotic-resistant bacteria has necessitated the search for new and effective antimicrobial compounds. This benzamide derivative helps synthesize novel antibiotics capable of combating resistant bacterial strains. Its role as an intermediate enables the creation of molecules with unique mechanisms of action, which are crucial in the arms race against rapidly evolving pathogens. Research into these new antibiotics holds the potential to address one of the most pressing public health challenges of our time.

Lastly, this compound is utilized in the field of neuropharmacology to create drugs that can modulate neurological functions. Neurological disorders, such as Alzheimer’s disease, Parkinson’s disease, and epilepsy, profoundly affect millions of lives globally. 4-Formyl-N-(2-Phenoxyethyl)benzamide aids in synthesizing neuroprotective agents that can potentially slow disease progression, ameliorate symptoms, or provide neuroprotection. By contributing to the development of these therapeutic agents, this compound is significant in advancing treatments for complex neurological conditions, thereby offering hope to patients and their families worldwide.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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