Inquiry Basket
Catalog | Product Name | CAS Number |
---|---|---|
BADC-01996 | N-Allyloxycarbonyl-1,2-diaminoethane hydrochloride | 1049722-41-9 |
N-Allyloxycarbonyl-1,2-diaminoethane hydrochloride is a protected diamine linker enabling selective conjugation in ADC synthesis, facilitating precise payload attachment and improved linker stability. | Inquiry | |
BADC-01999 | L-Val-D-Cit-PAB | 2226490-91-9 |
L-Val-D-Cit-PAB is a synthetic linker compound used in drug development and delivery systems, particularly in ADCs. The linker includes L-valine and D-citrulline, providing specific sites for enzymatic cleavage, and the para-aminobenzyloxycarbonyl group, which facilitates the release of the drug payload once the linker is cleaved within the target cell. This design allows for targeted and controlled drug release, enhancing the efficacy and reducing the toxicity of the therapeutic agents. | Inquiry | |
BADC-02003 | Alkyne-Val-Cit-PAB-FAM | 2748039-76-9 |
Alkyne-Val-Cit-PAB is a cleavable ADC linker. | Inquiry | |
BADC-02004 | Alkyne-Val-Cit-PAB-PNP | 2748039-77-0 |
Alkyne-Val-Cit-PAB-PNP is a cleavable ADC linker. | Inquiry | |
BADC-02005 | Boc-PEG2-Val-Cit-PAB-OH | 2055024-55-8 |
Boc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker. | Inquiry | |
BADC-02006 | Boc-PEG4-Val-Cit-PAB-OH | 2055024-54-7 |
Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker. | Inquiry | |
BADC-02007 | Fmoc-PEG2-Val-Cit-PAB-OH | 2055024-59-2 |
Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker. | Inquiry | |
BADC-02008 | Fmoc-PEG4-Val-Cit-PAB-OH | 2055024-58-1 |
Fmoc-PEG4-Val-Cit-PAB-OH is a protease-cleavable ADC linker widely used in targeted cancer therapies. Incorporating PEG and Val-Cit-PAB, it ensures stability in plasma and efficient payload release inside tumor cells. Ideal for antibody-drug conjugation. | Inquiry | |
BADC-02009 | NH2-PEG1-Val-Cit-PAB-OH | 2055024-63-8 |
NH2-PEG1-Val-Cit-PAB-OH serves as a cleavable ADC linker offering enhanced water solubility and controlled release. Featuring a Val-Cit-PAB peptide, it is activated by cathepsin B enzymes in tumor microenvironments. | Inquiry | |
BADC-02010 | NH2-PEG3-Val-Cit-PAB-OH | 2055024-62-7 |
NH2-PEG3-Val-Cit-PAB-OH is a cathepsin B-cleavable ADC linker widely used in antibody-drug conjugate (ADC) development. Featuring a PEG spacer for better pharmacokinetics, it enables precise drug release in tumor microenvironments. Ideal for lysosomal enzyme-triggered drug delivery. | Inquiry | |
BADC-02011 | NH2-PEG4-Val-Cit-PAB-OH | 2055024-61-6 |
NH2-PEG4-Val-Cit-PAB-OH is a PEGylated ADC linker with a Val-Cit dipeptide for enzyme-triggered release. This hydrophilic linker is ideal for ADC payload attachment, improving delivery precision and therapeutic performance. | Inquiry | |
BADC-02012 | L-Ornithinamide, N-[2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]acetyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- | 2003260-51-1 |
L-Ornithinamide, N-[2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]acetyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- functions as a multifunctional ADC linker enabling precise payload attachment and cleavable release in tumor microenvironments to improve ADC efficacy. | Inquiry | |
BADC-02013 | DBCO-S-S-acid | 2749426-25-1 |
DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
BADC-02014 | DBCO-PEG4-Val-Cit-PAB-PNP | 2226472-28-0 |
DBCO-PEG4-Val-Cit-PAB-PNP is a click-compatible ADC linker combining DBCO, PEG4 spacer, and a cleavable Val-Cit-PAB structure. Facilitates site-specific conjugation via SPAAC for enhanced ADC synthesis efficiency. | Inquiry | |
BADC-02017 | Azidoethyl-SS-ethylamine hydrochloride | 2712401-25-5 |
Azidoethyl-SS-ethylamine hydrochloride is a cleavable ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
BADC-02024 | Boc-Cystamine-Suc-OH | 946849-79-2 |
Boc-Cystamine-Suc-OH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It features a Boc (tert-butyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for attaching cytotoxic drugs to antibodies. This linker is designed to be stable in circulation but can be cleaved in the tumor microenvironment, allowing for controlled drug release and enhancing the effectiveness of ADCs. | Inquiry | |
BADC-02025 | Fmoc-Cystamine-Suc | 946849-80-5 |
Fmoc-Cystamine-Suc-OH is a compound used in solid-phase peptide synthesis (SPPS) and bioconjugation applications. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for constructing peptide sequences with specific functional groups. | Inquiry |