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Cleavable Linker
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Cleavable Linker

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Catalog Product Name CAS Number
BADC-01996 N-Allyloxycarbonyl-1,2-diaminoethane hydrochloride 1049722-41-9
N-Allyloxycarbonyl-1,2-diaminoethane hydrochloride is a protected diamine linker enabling selective conjugation in ADC synthesis, facilitating precise payload attachment and improved linker stability. Inquiry
BADC-01999 L-Val-D-Cit-PAB 2226490-91-9
L-Val-D-Cit-PAB is a synthetic linker compound used in drug development and delivery systems, particularly in ADCs. The linker includes L-valine and D-citrulline, providing specific sites for enzymatic cleavage, and the para-aminobenzyloxycarbonyl group, which facilitates the release of the drug payload once the linker is cleaved within the target cell. This design allows for targeted and controlled drug release, enhancing the efficacy and reducing the toxicity of the therapeutic agents. Inquiry
BADC-02003 Alkyne-Val-Cit-PAB-FAM 2748039-76-9
Alkyne-Val-Cit-PAB is a cleavable ADC linker. Inquiry
BADC-02004 Alkyne-Val-Cit-PAB-PNP 2748039-77-0
Alkyne-Val-Cit-PAB-PNP is a cleavable ADC linker. Inquiry
BADC-02005 Boc-PEG2-Val-Cit-PAB-OH 2055024-55-8
Boc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker. Inquiry
BADC-02006 Boc-PEG4-Val-Cit-PAB-OH 2055024-54-7
Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker. Inquiry
BADC-02007 Fmoc-PEG2-Val-Cit-PAB-OH 2055024-59-2
Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker. Inquiry
BADC-02008 Fmoc-PEG4-Val-Cit-PAB-OH 2055024-58-1
Fmoc-PEG4-Val-Cit-PAB-OH is a protease-cleavable ADC linker widely used in targeted cancer therapies. Incorporating PEG and Val-Cit-PAB, it ensures stability in plasma and efficient payload release inside tumor cells. Ideal for antibody-drug conjugation. Inquiry
BADC-02009 NH2-PEG1-Val-Cit-PAB-OH 2055024-63-8
NH2-PEG1-Val-Cit-PAB-OH serves as a cleavable ADC linker offering enhanced water solubility and controlled release. Featuring a Val-Cit-PAB peptide, it is activated by cathepsin B enzymes in tumor microenvironments. Inquiry
BADC-02010 NH2-PEG3-Val-Cit-PAB-OH 2055024-62-7
NH2-PEG3-Val-Cit-PAB-OH is a cathepsin B-cleavable ADC linker widely used in antibody-drug conjugate (ADC) development. Featuring a PEG spacer for better pharmacokinetics, it enables precise drug release in tumor microenvironments. Ideal for lysosomal enzyme-triggered drug delivery. Inquiry
BADC-02011 NH2-PEG4-Val-Cit-PAB-OH 2055024-61-6
NH2-PEG4-Val-Cit-PAB-OH is a PEGylated ADC linker with a Val-Cit dipeptide for enzyme-triggered release. This hydrophilic linker is ideal for ADC payload attachment, improving delivery precision and therapeutic performance. Inquiry
BADC-02012 L-Ornithinamide, N-[2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]acetyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- 2003260-51-1
L-Ornithinamide, N-[2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]acetyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- functions as a multifunctional ADC linker enabling precise payload attachment and cleavable release in tumor microenvironments to improve ADC efficacy. Inquiry
BADC-02013 DBCO-S-S-acid 2749426-25-1
DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-02014 DBCO-PEG4-Val-Cit-PAB-PNP 2226472-28-0
DBCO-PEG4-Val-Cit-PAB-PNP is a click-compatible ADC linker combining DBCO, PEG4 spacer, and a cleavable Val-Cit-PAB structure. Facilitates site-specific conjugation via SPAAC for enhanced ADC synthesis efficiency. Inquiry
BADC-02017 Azidoethyl-SS-ethylamine hydrochloride 2712401-25-5
Azidoethyl-SS-ethylamine hydrochloride is a cleavable ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-02024 Boc-Cystamine-Suc-OH 946849-79-2
Boc-Cystamine-Suc-OH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It features a Boc (tert-butyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for attaching cytotoxic drugs to antibodies. This linker is designed to be stable in circulation but can be cleaved in the tumor microenvironment, allowing for controlled drug release and enhancing the effectiveness of ADCs. Inquiry
BADC-02025 Fmoc-Cystamine-Suc 946849-80-5
Fmoc-Cystamine-Suc-OH is a compound used in solid-phase peptide synthesis (SPPS) and bioconjugation applications. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for constructing peptide sequences with specific functional groups. Inquiry
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