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Cleavable Linker
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Cleavable Linker

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Catalog Product Name CAS Number
BADC-01720 MC-PEG2-NH2 640267-62-5
MC-PEG2-NH2 is a maleimide-PEG2 amine ADC linker intermediate designed for thiol-specific conjugation and improved payload stability in antibody-drug conjugates. Keywords: ADC linker, maleimide linker, PEG spacer, thiol conjugation, payload delivery. Inquiry
BADC-01721 Val-Cit-PABC-Ahx-May TFA 2126749-75-3
Val-Cit-PABC-Ahx-May TFA is a trifluoroacetate salt form of a cleavable ADC linker featuring enzyme-sensitive Valine-Citrulline dipeptide for controlled payload release in antibody-drug conjugates. Keywords: ADC linker, cleavable linker, Val-Cit, TFA salt, enzyme-sensitive. Inquiry
BADC-01722 MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH 1802520-40-6
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01727 diSPhMC-Asn-Pro-Val-PABC-MMAE 2893871-68-4
diSPhMC-Asn-Pro-Val-PABC-MMAE is a cleavable peptide-based ADC linker designed for precise enzymatic cleavage and controlled payload release in antibody-drug conjugates, enhancing therapeutic efficacy. Keywords: ADC linker, cleavable linker, peptide linker, enzyme-sensitive, MMAE payload. Inquiry
BADC-01731 diMal-O-CH2COOH 1620837-47-9
diMal-O-CH2COOH is a bismaleimide ADC linker intermediate offering dual thiol-reactive sites for crosslinking and payload conjugation in antibody-drug conjugates, improving drug stability and delivery. Keywords: ADC linker, bismaleimide, dual conjugation, thiol reactive, crosslinker. Inquiry
BADC-01738 MC-Val-D-Cit-PAB-PNP 1350456-66-4
MC-Val-D-Cit-PAB-PNP is a protease-sensitive ADC linker with D-citrulline and self-immolative para-aminobenzyl (PAB) spacer, ensuring selective drug release and improved ADC safety profiles. Inquiry
BADC-01740 Mal-amido-PEG9-Val-Ala-PAB-SG3200 1817788-75-2
Mal-amido-PEG9-Val-Ala-PAB-SG3200 is a maleimide-based ADC linker with extended PEG spacer and protease-cleavable sequences, designed for precise antibody conjugation and controlled intracellular payload release. Inquiry
BADC-01741 AcLys-PABC-VC-Aur0101 intermediate-1 1609108-48-6
AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01745 MC-Val-Cit-PAB-NH-C2-NH-Boc 1616727-22-0
MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01746 MC-Gly-Gly-Phe-Gly-PAB-PNP 2632342-16-4
MC-Gly-Gly-Phe-Gly-PAB-PNP is a peptide ADC linker intermediate containing cleavable sequences for enzyme-triggered drug release, supporting controlled payload delivery in antibody-drug conjugates. Keywords: ADC linker, peptide linker, enzyme-cleavable, payload release, controlled delivery. Inquiry
BADC-01747 D-Val-D-Cit-PAB
D-Val-D-Cit-PAB is a synthetic linker compound used in drug development and delivery systems, particularly in ADCs. The linker includes D-valine and D-citrulline, providing specific sites for enzymatic cleavage, and the para-aminobenzyloxycarbonyl group, which facilitates the release of the drug payload once the linker is cleaved within the target cell. This design allows for targeted and controlled drug release, enhancing the efficacy and reducing the toxicity of the therapeutic agents. Inquiry
BADC-01749 EGGGG-PEG8-amide-bis(deoxyglucitol) 2842855-38-1
EGGGG-PEG8-amide-bis(deoxyglucitol) is a hydrophilic ADC linker with PEG8 spacer and sugar-based protective groups, enhancing solubility and biocompatibility for efficient payload conjugation in antibody-drug conjugates. Keywords: ADC linker, PEG linker, hydrophilic linker, sugar derivatives, payload conjugation. Inquiry
BADC-01754 Mal-Ala-Ala-PAB-PNP 2003260-14-6
Mal-Ala-Ala-PAB-PNP is a maleimide-functionalized peptide ADC linker intermediate with cleavable alanine-alanine sequence, enabling thiol-reactive conjugation and controlled payload release in antibody-drug conjugates. Keywords: ADC linker, maleimide linker, cleavable peptide, thiol conjugation, payload release. Inquiry
BADC-01764 4-Pentynoyl-Val-Ala-PAB-PNP 1956294-76-0
4-Pentynoyl-Val-Ala-PAB-PNP is an alkyne-functionalized peptide ADC linker enabling click chemistry conjugation and enzyme-triggered payload release in antibody-drug conjugates. Keywords: ADC linker, alkyne linker, peptide linker, click chemistry, enzyme-cleavable. Inquiry
BADC-01796 SCO-PEG3-Maleimide 2141976-35-2
SCO-PEG3-Maleimide is a strain-promoted cyclooctyne ADC linker with PEG3 spacer and maleimide group, facilitating rapid and selective thiol-reactive conjugation in antibody-drug conjugates for stable payload attachment. Keywords: ADC linker, SCO linker, PEG spacer, maleimide linker, thiol conjugation. Inquiry
BADC-01798 SCO-PEG3-NH2 2141976-29-4
SCO-PEG3-NH2 is a strain-promoted cyclooctyne PEG3 ADC linker featuring a primary amine group for bioorthogonal conjugation, supporting rapid and site-specific payload attachment in antibody-drug conjugates. Keywords: ADC linker, SCO linker, PEG spacer, amine group, bioorthogonal chemistry. Inquiry
BADC-01801 Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz 2914227-56-6
Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz is a peptide-PEG based ADC linker intermediate incorporating Gly-Gly-Phe-Gly sequence and PEG4 spacer, designed for enzyme-cleavable payload release in antibody-drug conjugates. Keywords: ADC linker, peptide linker, PEG spacer, enzyme-cleavable, controlled release. Inquiry
BADC-01803 Sco-peg2-NH2 2141976-34-1
Sco-peg2-NH2 is a strain-promoted cyclooctyne PEG2 ADC linker with amine functionality, enabling fast bioorthogonal conjugation and stable payload attachment in antibody-drug conjugates. Keywords: ADC linker, SCO linker, PEG spacer, amine linker, bioorthogonal chemistry. Inquiry
BADC-01815 Fmoc-Gly-Gly-allyl propionate 2766214-15-5
Fmoc-Gly-Gly-allyl propionate is a peptide-based ADC linker intermediate with orthogonal allyl protection, facilitating selective payload conjugation and enzyme-triggered release in antibody-drug conjugates. Keywords: ADC linker, peptide linker, allyl protection, enzyme-cleavable, bioconjugation. Inquiry
BADC-01830 Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA 2734877-83-7
Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) is a cleavable linker, which can be used to synthesize Antibody-Drug Conjugates (ADCs). Inquiry
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