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diSPhMC-Asn-Pro-Val-PABC-MMAE is a potent ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01727 | -- | $-- | Inquiry |
diSPhMC-Asn-Pro-Val-PABC-MMAE, a synthetic peptide-drug conjugate (PDC) customized for precise cancer therapy, unveils a plethora of applications within the oncology domain. Here are four key applications:
Targeted Cancer Therapy: The meticulously engineered diSPhMC-Asn-Pro-Val-PABC-MMAE zeroes in on cancer cells with unparalleled accuracy while preserving the integrity of healthy tissues. The peptide component steers the conjugate towards specific cancer markers, ensuring the direct delivery of the potent MMAE payload to malignant cells. This precise targeting not only mitigates side effects but also amplifies the efficacy of cancer treatments.
Antibody-Drug Conjugate Research: Embedded as a pivotal element in the advancement of antibody-drug conjugates (ADCs), diSPhMC-Asn-Pro-Val-PABC-MMAE merges the selectivity of antibodies with the potency of cytotoxic drugs. Scientists harness this compound to scrutinize the stability, effectiveness, and safety of prospective ADCs. These discoveries play a pivotal role in sculpting more robust and secure cancer therapies.
Combination Therapy Studies: In the domain of cancer investigation, diSPhMC-Asn-Pro-Val-PABC-MMAE emerges as an indispensable instrument for exploring innovative combination therapies. By amalgamating this conjugate with other therapeutic compounds, researchers can evaluate synergistic effects and fine-tune treatment protocols. This method has the potential to enhance treatment outcomes and circumvent the development of drug resistance.
Pharmacokinetic and Pharmacodynamic (PK/PD) Analysis: Researchers leverage diSPhMC-Asn-Pro-Val-PABC-MMAE for intricate PK/PD analyses to unravel its distribution, metabolism, elimination in the body, and its molecular-level mode of action. These analyses play a crucial role in determining optimal dosage regimens and maximizing therapeutic efficiency while minimizing adverse effects.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
