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EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01749 | -- | $-- |
EGGGG-PEG8-amide-bis(deoxyglucitol) is a versatile chemical compound with diverse applications in advanced bioscience. Here are four key applications:
Drug Delivery Systems: Unleashing the potential of EGGGG-PEG8-amide-bis(deoxyglucitol), researchers can revolutionize drug delivery, enhancing the stability and efficacy of therapeutic agents. The PEG component enhances drug solubility and bioavailability, making it a crucial element in nanoparticle-based drug delivery systems. By enabling targeted and sustained drug release, this compound plays a pivotal role in optimizing medication delivery strategies for maximal efficacy.
Bioconjugation: EGGGG-PEG8-amide-bis(deoxyglucitol) stands as a cornerstone in bioconjugation methodologies, offering a versatile platform for attaching a myriad of biomolecules, from peptides to proteins and antibodies to drug carriers or functional groups. With its multiple reactive sites, this compound facilitates flexible conjugation techniques, laying the groundwork for the creation of highly specific and functional biomaterials customized for diagnostics and therapeutic interventions with unparalleled precision, opening new avenues for advanced bioconjugation strategies.
Medical Imaging: Embracing the versatility of EGGGG-PEG8-amide-bis(deoxyglucitol), researchers can pioneer advancements in medical imaging by designing contrast agents that enhance imaging diagnostics. With its biocompatible and hydrophilic properties, this compound improves the circulation time and reduces the immunogenicity of imaging agents, thereby boosting the sensitivity and accuracy of modalities like MRI and CT.
Targeted Drug Delivery: Capitalizing on its ability to link targeting moieties, such as ligands or antibodies, EGGGG-PEG8-amide-bis(deoxyglucitol) empowers the development of targeted drug delivery systems. This strategic approach ensures the precise delivery of therapeutics to specific cells or tissues, minimizing off-target effects and maximizing therapeutic outcomes. Such targeted delivery strategies are essential in the realm of disease treatment, particularly in diseases like cancer, where precision and efficacy are paramount for successful treatment outcomes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
