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SCO-PEG3-NH2

CAS No.: 2141976-29-4

Cat No.: BADC-01798 4.5

SCO-PEG3-NH2 is a strain-promoted cyclooctyne PEG3 ADC linker featuring a primary amine group for bioorthogonal conjugation, supporting rapid and site-specific payload attachment in antibody-drug conjugates. Keywords: ADC linker, SCO linker, PEG spacer, amine group, bioorthogonal chemistry.

SCO-PEG3-NH2

Structure of 2141976-29-4

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ADC Linker

Molecular Formula

C17H30N2O5

Molecular Weight

342.43

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Delivery of 200+ ADCs annually;
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IUPAC Name

cyclooct-2-yn-1-yl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate

Canonical SMILES

C1CCC#CC(CC1)OC(=O)NCCOCCOCCOCCN

InChI

InChI=1S/C17H30N2O5/c18-8-10-21-12-14-23-15-13-22-11-9-19-17(20)24-16-6-4-2-1-3-5-7-16/h16H,1-4,6,8-15,18H2,(H,19,20)

InChIKey

GWBSPEPUZAYTKR-UHFFFAOYSA-N

Catalog	Product Name	CAS	Inquiry
BADC-01779	SCO-PEG2-Maleimide	2141976-23-8
BADC-01803	Sco-peg2-NH2	2141976-34-1
BADC-01796	SCO-PEG3-Maleimide	2141976-35-2
BADC-01854	SCO-PEG7-Maleimide	2143968-81-2

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Historical Records: (S)-2-((S)-2-(3-(2-(2-Azidoethoxy)ethoxy)propanamido)-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide | PROTAC BRD4 Degrader-12 | PROTAC BRD4 Degrader-10 | (((S)-1-(((4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)propanamido)benzyl)oxy)carbonyl)pyrrolidin-2-yl)methyl)(2-(methylsulfonyl)ethyl)carbamic acid | Val-Cit-PAB-OSBT | PROTAC BRD4 Degrader-9 | PROTAC BRD4 Degrader-13 | DBCO-PEG4-Val-Cit-PAB-PNP | Mal-di-PEG-Val-Cit-PAB | NH2-PEG4-Val-Cit-PAB-OH | SCO-PEG3-NH2

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