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Boc-Cystamine-Suc-OH - CAS 946849-79-2

Boc-Cystamine-Suc-OH - CAS 946849-79-2 Catalog number: BADC-02024

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Boc-Cystamine-Suc-OH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It features a Boc (tert-butyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for attaching cytotoxic drugs to antibodies. This linker is designed to be stable in circulation but can be cleaved in the tumor microenvironment, allowing for controlled drug release and enhancing the effectiveness of ADCs.

Category
ADC Linker
Product Name
Boc-Cystamine-Suc-OH
CAS
946849-79-2
Catalog Number
BADC-02024
Molecular Formula
C13H24N2O5S2
Molecular Weight
352.47
Purity
>99%
Boc-Cystamine-Suc-OH

Ordering Information

Catalog Number Size Price Quantity
BADC-02024 -- $-- Inquiry
Synonyms
4-(2-((2-t-Butyloxycarbonylaminoethyl)disulfanyl)ethylamino)-4-oxobutanoic acid; 2,2-Dimethyl-4,13-dioxo-3-oxa-8,9-dithia-5,12-diazahexadecan-16-oic acid; N2-t-Butyloxycarbonyl-2,2'-disulfanediyldiethanamine succinamic acid; 15,15-Dimethyl-4,13-dioxo-14-oxa-8,9-dithia-5,12-diazahexadecanoic acid
IUPAC Name
4-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyldisulfanyl]ethylamino]-4-oxobutanoic acid
Canonical SMILES
CC(C)(C)OC(=O)NCCSSCCNC(=O)CCC(=O)O
InChI
InChI=1S/C13H24N2O5S2/c1-13(2,3)20-12(19)15-7-9-22-21-8-6-14-10(16)4-5-11(17)18/h4-9H2,1-3H3,(H,14,16)(H,15,19)(H,17,18)
InChIKey
ZDIJUJORRFBJFP-UHFFFAOYSA-N
Density
1.2±0.1 g/cm3
Melting Point
73-81 °C
Appearance
White crystalline powder
Storage
Store at 2-8 °C
Boiling Point
595.6±45.0 °C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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