Cleavable Linkers
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Catalog Product Name CAS Number
BADC-01446 Fmoc-GGFG-OH 1817857-75-2
Fmoc-GGFG-OH is a protease cleavable linker used for the antibody-drug conjugate (ADC). Inquiry
BADC-01482 Fmoc-Val-Ala-OH 150114-97-9
Fmoc-Val-Ala-OH is a widely used cleavable peptide linker that can conveniently serve as a building block for the careful construction of peptide-directed therapeutics and pharmaceuticals. Its multifaceted nature holds great promise in combating a range of diseases, including but not limited to neoplastic diseases, autoimmune diseases, and potential infections. Inquiry
BADC-01586 Fmoc-Gly-Gly-Gly-Gly-OH 1001202-16-9
Fmoc-Gly-Gly-Gly-Gly-OH is an inherent constituent within the biomedical realm. It serves as a pivotal foundational constituent in the conduction of peptide and peptidomimetic synthesis. With its pervasive utilization in the domain of pharmaceutical research and investigation, particularly in the fields of oncology, immunology, and neuroscience, it evinces auspicious prospects for therapeutic application. Inquiry
BADC-00370 Phe-Lys(Fmoc)-PAB 2149584-03-0
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BADC-00371 Phe-Lys(Trt)-PAB 1116085-99-4
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BADC-00375 1-{[4-({4-[(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy]-4-oxobutyl}disulfanyl)butanoyl]oxy}-2,5-dioxopyrrolidine-3-sulfonic acid 98604-89-8
Bis-SS-C3-sulfo-NHS ester is a highly intricate and multifaceted chemical entity. Exhibiting remarkable therapeutic potential, this compound assumes a vital role in combatting an array of diseases, primarily through its adeptness at selectively targeting distinct molecular pathways. Inquiry
BADC-00376 bis(2,5-dioxopyrrolidin-1-yl) 4,4'-disulfanediyldibutanoate 98604-88-7
Inquiry
BADC-00377 Bis(NHS)PEG9 1008402-79-6
Bis(NHS)PEG9 is a non-cleavable 9-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-00378 Bis(NHS)PEG5 756526-03-1
Bis(NHS)PEG5 is a non-cleavable 5-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-00396 Ald-PEG4-PFP 1324007-10-4
Ald-PEG4-PFP is a widely used chemical entity in the biomedical field, epitomizing its utility in drug delivery and target identification. Its composition exhibits a noteworthy polyethylene glycol derivative dominated by pentafluorophenyl (PFP) ester groups that binds efficiently to proteins and antibodies. This innovation significantly contributes to the advancement of groundbreaking treatments and diagnostics specifically targeting diseases such as cancer and autoimmune diseases. Inquiry
BADC-00414 endo-BCN-PEG4-PFP ester 1421932-52-6
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BADC-00416 endo-BCN-PEG3-PFP ester 2101206-48-6
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BADC-00417 endo-BCN-PEG3-NHS ester 2101206-94-2
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BADC-00418 endo-BCN-PEG2-PFP ester 1421932-53-7
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BADC-00419 2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate 2243565-12-8
2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate is a small molecule compound with biological activity. It has been widely studied as a linker in ADC development. Inquiry
BADC-00426 Perfluorophenyl 2-(cyclooct-2-ynyloxy)acetate 886209-60-5
Perfluorophenyl 2-(cyclooct-2-ynyloxy)acetate is a cleavable ADC junction bridge for the synthesis of antibody drug conjugates (ADCs). It is a chemical compound used in click chemistry and bioconjugation applications. It features a cyclooctyne moiety, which is a reactive cyclic alkyne with a strained ring structure, making it highly reactive in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. The O-PFP (pentafluorophenyl) ester group is a reactive functional group that facilitates the attachment of this molecule to other biomolecules or surfaces. This compound is often used for labeling, imaging, or creating bioconjugates in chemical biology and drug development. Inquiry
BADC-00427 2,5-dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate 1425803-45-7
2,5-dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate is a promising biomedical chemical used in the treatment of various diseases. It exhibits potential therapeutic effects against inflammation, cancer, and microbial infections. This compound acts by targeting specific receptors and pathways, modulating cellular processes, and promoting desired therapeutic outcomes. Further research on its pharmacological properties and clinical applications shows immense potential for disease management and improved patient outcomes. Inquiry
BADC-00454 N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-L-alanine 1342211-31-7
MC-Val-Ala-OH is a promising dipeptidyl peptidase 4 (DPP-4) inhibitor. It demonstrates the potential to reduce the breakdown of incretin hormones by inhibiting DPP-4. This intervention promotes increases in glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) levels, representing a pathway to superior glycemic management. Inquiry
BADC-00456 2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate 1956318-90-3
Inquiry
BADC-00457 4-nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate 1887040-81-4
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