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2,5-dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate is a promising biomedical chemical used in the treatment of various diseases. It exhibits potential therapeutic effects against inflammation, cancer, and microbial infections. This compound acts by targeting specific receptors and pathways, modulating cellular processes, and promoting desired therapeutic outcomes. Further research on its pharmacological properties and clinical applications shows immense potential for disease management and improved patient outcomes.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00427 | -- | $-- | Inquiry |
Bioorthogonal Chemistry and Bioconjugation: 2,5-Dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate is widely used in bioorthogonal chemistry due to its strained alkyne moiety, which allows for rapid and specific reactions with azides via copper-free click chemistry. This enables the conjugation of biomolecules without interfering with native biological processes. Its utility in labeling, imaging, and tracking biomolecules in live cells and organisms makes it a valuable tool in chemical biology and molecular diagnostics.
Drug Delivery and Targeted Therapy: This compound is utilized in the design of targeted drug delivery systems, where the active drug can be selectively delivered to a specific tissue or cell type. By conjugating therapeutic agents to antibodies, peptides, or other targeting molecules through this linker, it ensures the precise delivery of drugs, minimizing off-target effects and enhancing therapeutic efficacy. Such applications are particularly relevant in the development of antibody-drug conjugates (ADCs) for cancer therapy.
Polymer and Material Science: 2,5-Dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate is employed in the synthesis of functionalized polymers and materials. Its reactive groups facilitate the incorporation of various functional moieties into polymer backbones, allowing for the development of advanced materials with tailored properties. These materials are useful in fields such as biocompatible coatings, drug delivery systems, and tissue engineering, where controlled functionality and reactivity are crucial.
Surface Modification and Immobilization: This compound is also used for surface modification and immobilization of biomolecules on solid supports. The strained alkyne group enables efficient attachment of proteins, enzymes, or other biomolecules onto surfaces through bioorthogonal reactions. This capability is critical for the development of biosensors, diagnostic devices, and bioanalytical platforms, where stable and specific immobilization is necessary for accurate detection and measurement of target analytes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
