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Cleavable Linker
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Catalog Product Name CAS Number
BADC-00458 4-nitrophenyl 2-(pyridin-2-yldisulfanyl)ethyl carbonate 874302-76-8
4-nitrophenyl 2-(pyridin-2-yldisulfanyl)ethyl carbonate features a cleavable disulfide bond and activated nitrophenyl carbonate group, facilitating efficient payload attachment and controlled release to boost ADC targeting and anti-cancer activity. Inquiry
BADC-00459 SPDP-PEG8-NHS 1252257-56-9
SPDP-PEG8-NHS is a heterobifunctional, cleavable PEG linker with NHS ester and pyridyl disulfide groups for stable antibody modification and disulfide exchange. The PEG8 spacer enhances hydrophilicity and reduces steric hindrance, improving ADC pharmacokinetics and solubility. Inquiry
BADC-00460 Pyridin-2-yldisulfanyl-PEG4-NHS 1305053-43-3
Pyridin-2-yldisulfanyl-PEG4-NHS is a heterobifunctional ADC linker designed for PEGylated, cleavable drug conjugation. The PEG4 spacer improves solubility and flexibility, while the NHS ester and pyridyl disulfide allow for site-specific thiol-reactive coupling in ADC and bioconjugate synthesis. Inquiry
BADC-00463 N-succinimidyl-6-(2-pyridyldithio)capronate 1824718-79-7
N-succinimidyl-6-(2-pyridyldithio)capronate offers efficient NHS ester and pyridyl disulfide groups for stable antibody conjugation and cleavable payload release, optimizing antibody-drug conjugate performance in targeted oncology applications. Inquiry
BADC-00464 N-succinimidyl-5-(2-pyridyldithio)valerate 317331-86-5
N-succinimidyl-5-(2-pyridyldithio)valerate features cleavable disulfide linkage and reactive NHS ester, ensuring selective payload conjugation and tumor-triggered release to enhance ADC cytotoxicity and safety profiles. Inquiry
BADC-00465 1-(4-methyl-4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid 663599-00-6
NO2-SPDMV-sulfo is a small molecule compound in the biomedical field. It is a potent drug that shows significant efficacy by selectively targeting key drug receptors. It has shown great promise in halting the progression of certain malignancies and inflammatory diseases. Inquiry
BADC-00469 1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid 663599-11-9
1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid is a cleavable ADC linker featuring disulfide bonds and NHS ester functionality. It enables stable antibody conjugation and selective intracellular payload release, improving ADC precision and therapeutic effect. Inquiry
BADC-00470 2,5-dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate 663599-10-8
2,5-dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate features cleavable disulfide and NHS ester groups, allowing precise antibody-payload conjugation and controlled intracellular release to enhance ADC targeting and cytotoxicity in cancer treatment. Inquiry
BADC-00471 3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate 890409-87-7
3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate enables stable antibody conjugation through NHS ester and disulfide chemistry, allowing tumor-triggered payload release and improved therapeutic efficacy in ADC cancer therapy. Inquiry
BADC-00472 1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-ioxopyrrolidine-3-sulfonic acid 663598-66-1
1-(4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid is a cleavable ADC linker facilitating antibody conjugation via NHS sulfonic acid and disulfide bonds, ensuring controlled payload release in tumor cells and enhanced ADC specificity and potency. Inquiry
BADC-00473 2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate 663598-61-6
2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate is a pyridyl disulfide-containing ADC linker with NHS ester function, designed for stable antibody attachment and selective intracellular release to improve antibody-drug conjugate therapeutic performance. Inquiry
BADC-00474 2,5-dioxo-1-(4-(pyridin-2-yldisulfanyl)pentanoyloxy)pyrrolidine-3-sulfonic acid 452072-27-4
2,5-dioxo-1-(4-(pyridin-2-yldisulfanyl)pentanoyloxy)pyrrolidine-3-sulfonic acid combines pyridyl disulfide and NHS sulfonic acid groups, facilitating effective antibody conjugation and intracellular payload release to optimize ADC potency and selectivity. Inquiry
BADC-00475 1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid 1193111-37-3
1-(2,5-dioxopyrrolidin-1-yloxy)-4-((5-nitropyridin-2-yl)disulfanyl)-1-oxobutane-2-sulfonic acid combines NHS ester and disulfide chemistries to ensure stable antibody conjugation and tumor-specific payload release, optimizing ADC stability and therapeutic outcomes. Inquiry
BADC-00476 2,5-dioxopyrrolidin-1-yl 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate 1193111-73-7
Dimethylamine-SPDB is a small molecule biopharmaceutical compound. It inhibits viral replication and pathogenesis by targeting enzymes, demonstrating its prowess as a powerful antagonist of viral infections, including influenza and hepatitis. Furthermore, it holds great promise in the field of oncology, fighting malignant tumors by elastically destroying the growth and proliferation of malignant cells. Inquiry
BADC-00478 1-(4-((5-(dimethylcarbamoyl)pyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid 663599-07-3
DMAC-SPDB-sulfo is an effective small molecule reagent. Its efficacy is primarily due to its selective mediation of key enzyme cascades and receptor signaling pathways, which are critical for targeted disease progression. This breakthrough bioactive compound has great potential to intervene in specific diseases. Inquiry
BADC-00479 1-(4-((5-nitropyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid 663598-89-8
1-(4-((5-nitropyridin-2-yl)disulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid is an ADC linker containing cleavable disulfide bonds and NHS ester functionalities, facilitating stable antibody conjugation and tumor-specific payload release for enhanced ADC selectivity and cytotoxicity. Inquiry
BADC-00480 3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)butanoate 890409-86-6
3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)butanoate is a cleavable ADC linker supporting efficient conjugation via NHS ester and disulfide chemistry, enabling controlled intracellular drug release and improved therapeutic performance of antibody-drug conjugates. Inquiry
BADC-00482 2,5-dioxo-1-(4-(pyridin-2-yldisulfanyl)butanoyloxy)pyrrolidine-3-sulfonic acid 1628113-16-5
SPDB-sulfo is a small molecule compound. This compound is effective against bacterial invasion, including pneumonia, respiratory infections, and urinary tract infections. It exhibits its good antibacterial abilities. Inquiry
BADC-00483 2,5-dioxopyrrolidin-1-yl 4-((5-(dimethylcarbamoyl)pyridin-2-yl)disulfanyl)butanoate 663599-05-1
DMAC-SPDB is a bioactive compound. It blocks signaling pathways associated with cancer and inflammation, exerting its influence as a targeted enzyme inhibitor. Furthermore, it shows decent proficiency in regulating the harmonious balance of enzymatic reactions associated with metabolic dysfunction. Inquiry
BADC-00484 N-succinimidyl 4-(5-nitro-pyridin-2-yldithio)-pentanoate 663598-85-4
N-succinimidyl 4-(5-nitro-pyridin-2-yldithio)-pentanoate is a disulfide-based ADC linker with NHS ester activity, facilitating efficient payload attachment and controlled cleavage within tumor cells. This enhances antibody-drug conjugate stability and targeted drug delivery. Inquiry
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